Background: Research on cancer in wild animals provides important insights into the mechanisms of carcinogenesis. Histiocytic sarcomas comprise a rare malignant macrophage-dendritic cell lineage neoplasm in wildlife. This study reports a case of histiocytic sarcoma in the small intestine of a collared peccary (Pecari tajacu), describing its clinical, anatomopathological, and immunohistochemical aspects.
View Article and Find Full Text PDFIntroduction: Neuropathy is an important feature of leprosy, a chronic infection caused by that mainly affects the skin and peripheral nerves. There is a rare and atypical form called the pure neural form, which is manifested only by changes in the nerves, without lesions on the skin, which makes early diagnosis difficult. If left untreated, neuropathy can lead to deformities and disabilities.
View Article and Find Full Text PDFData Brief
October 2025
This dataset includes the compositional information of = 1778 geoarchaeological samples of green phosphate minerals sourced from three major Iberian deposits with evidence of prehistoric mining: Aliste, Terena, and the Gavà Mines. It has been used to develop a data-driven framework that integrates portable X-ray fluorescence (p-XRF) analysis and machine learning (ML), to determine the provenance of archaeological artifacts based on its elemental composition. In addition, a mineralogical analysis by X-ray diffraction (XRD) of a subset ( = 249; n_Aliste = 122, n_Terena = 47, n_Gavà = 80) was conducted to complement the geochemical characterisation of the sample.
View Article and Find Full Text PDFBackground: Early identification of children at risk of asthma attacks is important for optimizing treatment strategies. We aimed to integrate salivary microbiome and serum inflammatory mediator profiles with asthma attacks history to develop a comprehensive predictive model for future attacks.
Methods: This study contained a discovery (SysPharmPediA) and a replication phase (U-BIOPRED).
Laboratory-raised mice live approximately seven times longer and healthier lives compared to their wild counterparts, due to a standardized healthy diet and limited exposure to environmental stressors. Aging is associated with increased inflammation and microbial dysbiosis. Collectively, these influence microbiota evolution and may contribute to the enrichment in pathobiont frequency observed in old age.
View Article and Find Full Text PDFCrit Care Sci
August 2025
Restoring immune homeostasis after an acute insult is essential for achieving a full recovery from an acute respiratory distress syndrome episode. Immune monitoring tools that are not exclusive to the blood compartment are in great demand to help guide treatment decisions. In this longitudinal study, we report a case of severe malaria-associated acute respiratory distress syndrome supported by venovenous extracorporeal membrane oxygenation.
View Article and Find Full Text PDFFront Sports Act Living
July 2025
Introduction: Rating of perceived exertion (RPE) is widely used for assessing training load in sports due to its validity, simplicity, and utility. Despite its broad application, the diverse contexts and methodologies in which it is used warrant a comprehensive review of the existing evidence.
Objective: This scoping review aims to map the current evidence on the use of RPE, focusing on its application, measurement methods, and reliability across different continuous sports.
This study aimed to determine the prevalence of antibodies against equine brucellosis in three distinct equid groups (farm animal, urban carthorse, and sport horse) in Western Pará, Brazil, and to identify associated risk factors. A cross-sectional study, involving 75 farms across 14 municipalities, sampled 1069 equids composed of urban carthorses and sport horses. Serum samples were tested for antibodies against spp.
View Article and Find Full Text PDFProg Mol Biol Transl Sci
July 2025
In recent years, the pursuit of efficient, reliable, customizable and sustainable power sources for wearable, ingestible and implantable (WII) biosensing technologies has intensified, aiming at effective energy management. This chapter overviews the recent developments on advanced energy storage systems for application as power sources in WII biosensing technologies. The progress in energy storage and harvesting technologies will be highlighted, ranging from batteries, supercapacitors and biofuel cells to wireless power transfer systems and self-powered energy harvesting/storage devices.
View Article and Find Full Text PDFAn Acad Bras Cienc
July 2025
Decommissioning Offshore Floating Production Storage and Offloading (FPSO) platforms is a process that requires technical expertise in a variety of technical endeavors. The mooring systems of FPSO platforms use high-tenacity polyester yarn, which is based on high molecular weight polyethylene terephthalate (PET). They are of high value and shouldn't be thrown away like any other trash.
View Article and Find Full Text PDFInt J Pharm
September 2025
In Colorectal Cancer (CRC), precise tumor imaging is crucial for detection but remainschallenging. R-phycoerythrin (R-PE), a highly fluorescent protein from red algae, shows potential for this purpose but its instability in aqueous environments limits direct use.Thus, nanoencapsulationcould be a promising strategy to overcome this limitation.
View Article and Find Full Text PDFGlob Heart
July 2025
Background: The prevalence of hypertension (HT) and blood pressure (BP) control varies among ethnic-racial groups, but studies on this issue and correlations between BP and body mass index (BMI) in the black Brazilian population are scarce.
Methods: Cross-sectional study in individuals included in the First Brazilian Hypertension Registry. Relationships between variables were analysed by a binary logistic regression analysis.
Functional electrical stimulation (FES) is commonly used in rehabilitation for its ability to activate muscle groups and functionally apply them. One of the most popular applications of FES is cycling for its safety and proven increase in users' health and quality of life. However, some challenges are intrinsic to the cycling application, among them, finding the best parameters of electrical stimulation to optimize the benefits for each user.
View Article and Find Full Text PDFThe textile products have a significant impact on the environment in terms of water, energy and waste disposal. Thus, recycling technology reduces waste and new raw material use. This mini-review aims to explore the trends in sustainable yarn development that address the use of pre- and post-consumer textiles.
View Article and Find Full Text PDFStem cell-derived secretome and exosomes present a promising cell-free strategy for tissue repair and wound healing. This study aimed to isolate and characterize, for the first time, exosomes derived from rat hair follicle stem cells (rHFSCs) and to evaluate their wound-healing potential alongside rHFSC secretome. Exosomes were isolated via ultracentrifugation and characterized using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR), biomarker profiling and protein quantification.
View Article and Find Full Text PDFJaundice is a common presentation of malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an adaptive or maladaptive response to spp. infection.
View Article and Find Full Text PDFMarine and salt marsh sediments contain large amounts of organic carbon (OC) and are therefore important in the global carbon cycle. Here, we collated previously published and unpublished measurements of sediment OC in marine and salt marsh sediments in European regional seas (EURO-CARBON; available at https://doi.org/10.
View Article and Find Full Text PDFSorghum-associated arthrogryposis and axonopathy is a rare congenital condition reported in ruminants and horses. Here, we describe the epidemiologic, clinical, and pathologic aspects of nine outbreaks of this condition in beef cattle in midwestern and southeastern Brazil (2014-2023). These regions are the most productive grain sorghum areas, where livestock producers use the straw extensively, producing a high regrowth during drought periods.
View Article and Find Full Text PDF(tropical horse tick) is a tick species commonly found parasitizing horses and other equids in the Amazon region, causing economic losses. Currently, tick control is based on chemical acaricides, usually in a power formulation for topical use. However, its indiscriminate use results in the emergence of resistant tick lineages.
View Article and Find Full Text PDFVet Res Commun
May 2025
Progressive syndrome of acquired dental disease (PSADD) is common in domestic rabbits and is often associated with chronic gingivitis, which compromises quality of life. Conventional treatment involves prolonged use of antimicrobials and anti-inflammatories, which may cause resistance and adverse effects. Cold atmospheric plasma (CAP) has antimicrobial, anti-inflammatory and regenerative properties, suggesting its therapeutic potential.
View Article and Find Full Text PDFIntroduction: Peripheral nerve injuries remain a significant clinical challenge, particularly in severe neurotmesis injuries requiring complex therapeutic interventions to restore functionality. This study aimed to evaluate the pro-regenerative potential of combining neural guide conduits with conditioned medium from olfactory mucosa mesenchymal stem cells, compared to gold-standard surgical techniques.
Methods: The study was conducted using a validated ovine model of common peroneal nerve injury.
This report describes the first documented case of intracerebral hemorrhage (ICH) in a horse following Bothrops snakebite envenomation. A 3-year-old mare developed acute kidney injury, systemic hemorrhage, and neurological signs before euthanasia. Postmortem findings confirmed massive ICH with intralesional venom identified by immunohistochemistry.
View Article and Find Full Text PDFArq Bras Cardiol
April 2025
Background: There is a strong association between hypertension and cerebrovascular disease, mainly with stroke and cognitive impairment. However, but the mechanistic of this relationship are not completely understood.
Objective: To analyze the relationship of central, peripheral blood pressure (BP) and arterial stiffness, with intracranial pressure (ICP) in long-term chronic hypertensive patients.
Watercress is a cruciferous vegetable and the primary natural source of phenylethyl isothiocyanate (PEITC), a powerful health-promoting agent. Conventional extraction of PEITC relies on harmful solvents, which limits sustainability. This study introduces a novel, solvent-free method-microwave hydrodiffusion and gravity (MHG)-to extract PEITC from watercress by-products (WCBP).
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