Publications by authors named "Amanda K Weaver"

Coccidioidomycosis ("Valley fever") is a fungal disease that causes a wide range of illness severity in animals and people. Here, we use U.S.

View Article and Find Full Text PDF

Coccidioidomycosis is an emerging fungal infection caused by inhalation of spp. spores. While airborne dispersal is critical to transmission, limited recovery of the pathogen from air has hindered understanding of the aerosolization and transport of spores.

View Article and Find Full Text PDF

Background: Coccidioidomycosis (Valley fever) occurs when animals and humans inhale spores of Coccidioides spp, soil-dwelling fungi of the southwestern United States (US). The spatial epidemiology of coccidioidomycosis is poorly understood due to irregular detection of Coccidioides in soil, disease underdiagnosis, and lack of nationwide mandatory reporting. Data on seroreactivity to Coccidioides among dogs-which are highly susceptible to coccidioidomycosis, widespread across the US, and have limited travel-may strengthen our understanding human disease risk.

View Article and Find Full Text PDF

Coccidioidomycosis, an emerging fungal disease in the southwestern United States, exhibits pronounced seasonal transmission, yet the influence of current and future climate on the timing and duration of transmission seasons remains poorly understood. We developed a distributed-lag Markov state transition model to estimate the effects of temperature and precipitation on the timing of transmission season onset and end, analysing reported coccidioidomycosis cases ( = 72 125) in California from 2000 to 2023. Using G-computation substitution estimators, we examined how hypothetical changes in seasonal meteorology impact transmission season timing.

View Article and Find Full Text PDF

Background: Coccidioidomycosis, caused by inhalation of spp. spores, is an emerging infectious disease that is increasing in incidence throughout the southwestern US. The pathogen is soil-dwelling, and spore dispersal and human exposure are thought to co-occur with airborne mineral dust exposures, yet fundamental exposure-response relationships have not been conclusively estimated.

View Article and Find Full Text PDF
Article Synopsis
  • Coccidioidomycosis is a fungal infection mainly transmitted through inhaling spores, but studying its airborne aspects has been difficult due to low recovery rates from air samples.
  • Researchers used uncrewed aircraft systems (UAS) with air samplers to capture and analyze spores in eastern San Luis Obispo County, California, where the fungus is present in soil.
  • During September 2023, they conducted 41 flights and found fungal DNA in 2 out of 41 air samples, marking the highest airborne detection known, which could advance knowledge of fungal dispersal in challenging environments like dust storms and wildfires.
View Article and Find Full Text PDF

Coccidioidomycosis, a fungal disease caused by soil-borne spp., exhibits pronounced seasonal transmission, with incidence in California typically peaking in the fall. However, the influence of climate on the timing and duration of transmission seasons remains poorly understood.

View Article and Find Full Text PDF

Unlabelled: The frequency and severity of wildfires in the Western United States have increased over recent decades, motivating hypotheses that wildfires contribute to the incidence of coccidioidomycosis, an emerging fungal disease in the Western United States with sharp increases in incidence observed since 2000. While coccidioidomycosis outbreaks have occurred among wildland firefighters clearing brush, it remains unknown whether fires are associated with an increased incidence among the general population.

Methods: We identified 19 wildfires occurring within California's highly endemic San Joaquin Valley between 2003 and 2015.

View Article and Find Full Text PDF

Emerging evidence supports a link between environmental factors-including air pollution and chemical exposures, climate, and the built environment-and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission and coronavirus disease 2019 (COVID-19) susceptibility and severity. Climate, air pollution, and the built environment have long been recognized to influence viral respiratory infections, and studies have established similar associations with COVID-19 outcomes. More limited evidence links chemical exposures to COVID-19.

View Article and Find Full Text PDF

Complex interactions within multitrophic communities are fundamental to the evolution of individual species that reside within them. One common outcome of species interactions are fitness trade-offs, where traits adaptive in some circumstances are maladaptive in others. Here, we identify a fitness trade-off between fecundity and survival in the cynipid wasp that induces multichambered galls on the stem of its host plant .

View Article and Find Full Text PDF

Anthropogenic environmental change is predicted to disrupt multitrophic interactions, which may have drastic consequences for population-level processes. Here, we investigate how a large-scale human-mediated disturbance affects the abundance of North America's most venomous caterpillar species, Megalopyge opercularis. Specifically, we used a natural experiment where netting was deployed to cover the entire canopies of a subset of mature southern live oak trees (Quercus virginiana) to exclude urban pest birds (grackles and pigeons), throughout an 8.

View Article and Find Full Text PDF