Publications by authors named "Alexander D Doudt"

Importance: Fluorescence-guided surgery aims to improve intraoperative identification of vital structures. Rizedisben is a myelin-binding fluorophore that fluoresces in the blue light (370-425 nm) spectrum to improve intraoperative nerve identification.

Objective: To determine the optimal safe and clinically effective dose of rizedisben for sustained intraoperative fluorescence of nerve structures.

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Article Synopsis
  • Radical cystectomy (RC) can significantly affect the quality of life (HRQOL) for patients, many of whom are or were smokers, influencing preoperative counseling.
  • Researchers analyzed data from a study that tracked HRQOL in RC patients over 2 years, using various measures to assess different aspects of their quality of life before and after the procedure.
  • The results showed that current smokers had worse overall quality of life and more pain post-surgery compared to former and never smokers, highlighting the need for tailored counseling for smoking patients regarding their recovery.
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Purpose: Several graft materials are available for use in the treatment of urethral stricture disease. Placental membrane is being used in a variety of settings as a graft in wound healing and tissue repair. We aim to evaluate the effect of implanting decellularized human placental membrane into rabbit urethras.

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Stress urinary incontinence following radical prostatectomy can have a significant impact on a man's quality of life. Male slings offer a perceived minimally invasive treatment option and do not require the manual dexterity necessary to operate an artificial urinary sphincter. In this review, we outline the history of male slings and discuss the various fixed and adjustable slings that are available on the market.

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Background: The gold standard treatment for primary obstructive megaureter (POM) with declining renal function, worsening obstruction, or recurrent infections is ureteral reimplantation with or without tapering. In infants, open surgery can be technically demanding and associated with significant morbidity. We conducted a systematic review of the literature with special interest in endoscopic management of POM and its outcomes.

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Of all patients who have vasectomies performed in the United States, upwards of 6% will pursue a vasectomy reversal. Currently, the gold-standard reversal procedure is a microscopic vasovasostomy utilizing either a one or two-layer vasal anastomosis. Unfortunately, most urologists do not perform these procedures as they require extensive training and experience in microsurgery.

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Background: Abdominoscrotal hydrocele (ASH) is an uncommon condition characterized by a fluid-filled mass with inguinoscrotal and abdominal components. Controversy exists regarding the best management. We conducted a systematic review of the literature with special interest in presentation, management and outcomes.

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