Identification, Quantification, and Antioxidant Evaluation of Phenolic Compounds from Colored (L.) Roots Using UHPLC-DAD-ESI-MS/MS.

This study investigates the phenolic composition and antioxidant potential of root extracts from three varieties (green, red, and orange) using ultra-high-performance liquid chromatography coupled with diode array detection and electrospray ionization-tandem mass spectrometry (UHPLC-DAD-ESI-MS/MS). Phenolic compounds were extracted with a hydromethanolic solvent and quantified by spectrophotometric assays, while antioxidant activity was assessed through DPPH, ABTS, iron III reduction, hydroxyl radical, and nitric oxide scavenging methods. A total of 26 compounds were identified, including piscidic acid, epicatechin-3--gallate, and isovitexin, with several phenolics newly reported for roots.

Probing defect formation in sulfur-annealed graphene for TMDC integration.

The integration of graphene with other 2D materials has been extensively studied over the past decade to realize high-performance devices unattainable with single materials. Graphene-transition metal dichalcogenides (TMDCs) such as MoS, WS, MoSe, and WSe vertical heterostructures have demonstrated promise in numerous electronic and optoelectronic applications due to the wide bandgap range and strong light-matter interaction in TMDCs, and the ability to form electrostatically tunable junctions with graphene. However, conventional methods for TMDCs growth, including chemical vapor deposition (CVD), electrodeposition, and atomic layer deposition (ALD), require high temperatures, which can degrade graphene's electrical and structural properties.

Association of antiphospholipid syndrome with infective endocarditis and sepsis induced by Staphylococcus aureus: A U.S. nationwide inpatient sample analysis.

BackgroundAntiphospholipid syndrome (APS) predisposes patients to thrombosis and cardiac valve lesions such as Libman-Sacks endocarditis. These vegetations are sterile yet can provide a nidus for infection; the risk of infective endocarditis (IE) and other serious infections in APS patients remains poorly quantified in large populations, representing a knowledge gap.ObjectiveTo quantify the risk of the primary outcome, IE, and secondary outcomes of MRSA sepsis and MSSA sepsis, associated with APS using a large, nationally representative inpatient database.

An Unusually Huge Keloid Complicating a Unilateral Otoplasty.

Giant recurrent auricular keloids, particularly those complicated by donor-site involvement, present significant therapeutic challenges due to aggressive fibroblast biology and high recurrence rates. We report a complex case of a 15-year-old female who developed a massive recurrent auricular keloid with associated abdominal donor-site keloid following otoplasty and subsequent skin grafting. Initial otoplasty at age 10 was complicated by keloid formation, requiring excision and abdominal full-thickness grafting.

Evaluating Outcomes of Over-Expanding Versus Conventional Sizing in transcatheter aortic valve replacement for Borderline Aortic Annulus: A Meta-Analysis.

Approximately 20-40% of patients that present for transcatheter aortic valve replacement (TAVR) with a balloon-expandable (BE) transcatheter heart valve (THV) fall into a borderline aortic annulus size (BAAS). There are potential benefits to over-expanding an under-sized THV (OE-THV) in such cases that include reduced electrical disturbances and annular injury at the expense of increased paravalvular leak (PVL). We conducted a meta-analysis of data comparing conventional sized vs OE-THV strategy for BAAS and review the literature for BE-THV in such cases.

Penetrating Sphenoid Sinus Injuries in Children: A Comprehensive Literature Review.

Penetrating foreign bodies in the pediatric sphenoid sinus are exceptionally rare and pose significant diagnostic and surgical challenges due to the sinus's proximity to critical neurovascular structures. We present the case of an 11 year-old boy who sustained a penetrating injury from a 7 mm bullet that entered through the floor of the frontal sinus, traversed the ethmoid sinus, and lodged in the right sphenoid sinus near the carotid canal and optic nerve. Initial assessment revealed hemodynamic stability and no active bleeding or neurological deficits.

Eco-Friendly Extraction of Sustainable and Valorized Value-Added Products From Macroalgae: A Holistic Technoeconomic Analysis.

The present work conducts a detailed technoeconomic analysis of an environmentally friendly zero-waste biorefinery process to valorize marine macroalgae into different sustainable value-added products. The proposed sequential fully integrated process yielded 34.89% mineral-rich water extract (MRWE), 2.

Balloon valvuloplasty and transcatheter aortic valve replacement aortofemoral bypass grafts: A case report and review of literature.

Background: Transcatheter aortic valve replacement (TAVR) can be performed through multiple access sites with the preferred approach being transfemoral. In patients with severe peripheral arterial disease and previous grafts, the safety of transfemoral access direct graft puncture, especially when performed twice within a short period, remains unclear compared to alternative access methods. We present a case demonstrating the safety and efficacy of direct graft puncture for transfemoral access during balloon aortic valvuloplasty (BAV) and TAVR.

Racial disparities in cardiovascular manifestations among patients with sickle cell trait: analysis of national inpatient sample data (2016-2020).

Sickle cell trait (SCT) is a condition that affects up to 3 million individuals and 10% of African Americans (AA) in the United States (U.S.).

Cancer-Associated Venous Thromboembolism Among Hospitalized Patients with Solid and Hematological Malignancies: A Comprehensive National Study.

Introduction: Venous thromboembolism (VTE) is a major cause of non-cancer-related mortality in cancer patients. Understanding how demographic factors and cancer types influence VTE risk is critical for developing prevention strategies. This study investigates the incidence of VTE in a large cancer patient population, focusing on gender, race, and differences between solid and hematological malignancies.

Predictors of complications and extended length of stay following percutaneous transluminal renal artery angioplasty.

Patients with renal artery stenosis (RAS) who fail medical management may be evaluated for Percutaneous transluminal renal artery angioplasty/stenting (PTRA/S). Comorbidities increasing the risk of complications following PTRA have not been explored well. Patients undergoing PTRA/S for RAS were sampled using National Inpatient Sample (NIS) Database.

Impact of Rhinoplasty on Nasal Breathing and Olfactory Function: A Longitudinal Prospective Cohort Study.

Introduction: Rhinoplasty surgery involves multiple specialties and often leads to respiratory and olfactory complaints. This study examines the impact of rhinoplasty on nasal function and patient satisfaction, aiming to enhance quality of life.

Objective: To assess the effect of rhinoplasty on nasal breathing and olfactory function.

Seaweed valorization as anaerobic co-substrate with fat, oil, and grease: Biomethane potential and microbial dynamics.

The present study explored the anaerobic co-digestion (AcD) of seaweed Gracilaria vermiculophylla with fat, oil, and grease (FOG) at 75, 50, and 25 % w/w of volatile solids (VS). Mono-digestion of FOG and SW led to a methane production of 133 and 109 mL/(g.d) with 40 days lag-phase, lower than 235 mL/(g.

Angiofibrolipoma in the Head and Neck Region: A Case Report and Literature Review.

Angiofibrolipomas are rare, benign soft tissue tumors composed of mature fat cells, blood vessels, and fibrous connective tissue. Typically occurring in subcutaneous locations, this case report presents a unique instance of an angiofibrolipoma arising in the pharynx. According to our review of the literature, it is the second reported case in the pharynx and the sixth in the head and neck region.

Systemic sclerosis and acute heart failure in prosthetic heart valve patients: A retrospective analysis.

Background: Acute heart failure in patients with prosthetic heart valves is a complex problem with clinical and therapeutic challenges. Systemic sclerosis is a chronic autoimmune disease frequently associated with valvular abnormalities. The association between systemic sclerosis and acute heart failure in patients with prosthetic heart valves remains understudied.

Has the time finally come for green oleochemicals and biodiesel production using large-scale enzyme technologies? Current status and new developments.

With the growth of the chemical industry over the last decade, the need for cheaper (and more environmentally friendly) alternatives to petrochemicals of ever-increasing cost has grown steadily. Oleochemicals and biodiesel (OC/BD) are considered as green alternatives to petroleum derivatives, because they come from renewable oils and fats. OC/BD are currently produced by the traditional energy intensive chemical catalyzed methods, which have several economic and environmental drawbacks.

Using novel machine learning tools to predict optimal discharge following transcatheter aortic valve replacement.

Background: Although transcatheter aortic valve replacement has emerged as an alternative to surgical aortic valve replacement, it requires extensive healthcare resources, and optimal length of hospital stay has become increasingly important. This study was conducted to assess the potential of novel machine learning models (artificial neural network and eXtreme Gradient Boost) in predicting optimal hospital discharge following transcatheter aortic valve replacement.

Aim: To determine whether artificial neural network and eXtreme Gradient Boost models can be used to accurately predict optimal discharge following transcatheter aortic valve replacement.

Incidence and Pattern of Mandibular Impacted 3 Molars and Their Relationship with the Mandibular Canal in Population of Jizan Province of Saudi Arabia: A Retrospective Radiographic Study.

Introduction: Impacted mandibular third molars pose challenges in dental practice, often requiring surgical intervention. This retrospective study aims to analyze the demographics, impaction patterns, and anatomical relationships of impacted mandibular third molars among Saudi patients.

Methodology: Data from 722 patients visiting the Department of Maxillofacial Surgery and Diagnostic Sciences at Jizan University were retrospectively analyzed.

Monoclonal Gammopathy of Undetermined Significance and Associated Cardiovascular Outcomes in a Hospital Setting-A Fresh Perspective.

There is a paucity of data on the cardiovascular implications of monoclonal gammopathy of undetermined significance, especially among hospitalized patients. Our study aimed to investigate the association between MGUS and cardiovascular outcomes in a hospital setting using the National Inpatient Sample database. MGUS patients were sampled using ICD-10 codes.

Exploring the Relationship Between Cannabis Use and COVID-19 Outcomes.

Cannabis use is becoming increasingly prevalent worldwide, yet the full spectrum of its effects largely remain unknown. Although cannabis have immunomodulatory properties, there remains a significant gap in our understanding of the potential impact of marijuana use on COVID-19 outcomes. The purpose of this study is to evaluate the effect of chronic cannabis use on severe COVID-19.

Collagen-Based Bailout Compared to Suture-Mediated Vascular Closure Alone During Transcatheter Aortic Valve Replacement.

Background: Hemostasis for transfemoral transcatheter aortic valve replacement (TAVR) is typically achieved using a suture-mediated vascular closure device (VCD) prior to large-bore sheath insertion (preclosure technique). Recently, the addition of a hybrid closure technique using a preclose technique with the addition of a collagen-plug VCD after sheath removal in cases of failed hemostasis has been utilized.

Methods: Data were collected from the Northwell TAVR registry, including 3 high-volume TAVR centers.

Antimicrobial and Antibiofilm Activity of Monolaurin against Methicillin-Resistant Isolated from Wound Infections.

Background: Methicillin-resistant (MRSA) is one of the major pathogens associated with life-threatening infections, showing resistance to various antibiotics. This study aimed to assess the influence of monolaurin on biofilm-forming MRSA.

Methods: The agar dilution method determined the minimum inhibitory concentration (MIC) of monolaurin against MRSA isolates and explored its impact on the resistance profile of selected antibiotics.