Dieulafoy's lesion is a rare but potentially life-threatening cause of upper gastrointestinal (UGI) bleeding. It is characterized by an abnormally large, tortuous artery in the submucosa that can erode the overlying mucosa and cause sudden, severe hemorrhage. While commonly found in the stomach, Dieulafoy's lesions in the esophagus are extremely rare and pose a diagnostic and therapeutic challenge.
View Article and Find Full Text PDFJ Cardiopulm Rehabil Prev
November 2023
Purpose: Chronic kidney disease (CKD) is common in heart failure (HF). Chronic kidney disease often worsens the prognosis and impairs the management of patients with HF. Chronic kidney disease is frequently accompanied by sarcopenia, which limits the benefits of cardiac rehabilitation (CR).
View Article and Find Full Text PDFCrit Rev Oncol Hematol
January 2021
Targeting the immune system with immune checkpoint inhibitors (ICI) to treat cancer has been lately adopted with a significant improvement of patients' survival. In parallel, the incidence of malignancy in chronic kidney disease (CKD) patients is increasing, but solid evidence concerning the efficacy and safety of ICI in this population is lacking. Moreover, the use of these agents as immunity boosters in kidney graft recipients treated with immunosuppressors is still controversial.
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