Prevalence and Clinical Implications of Sleep Apnea in Hypertrophic Cardiomyopathy.

Importance: Sleep disordered breathing (SDB) is a well-established contributor to cardiovascular morbidity, mediated by intermittent hypoxemia, autonomic dysregulation, and endothelial dysfunction. Patients with hypertrophic cardiomyopathy (HCM) may be especially at risk for SDB, but the clinical impact of SDB in this population remains unclear.

Objective: To define the prevalence and subtypes of SDB in HCM and examine their association with echocardiographic parameters and cardiac biomarker expression.

High-Power Short-Duration Ablation Versus Conventional Power Ablation in Pulmonary Vein Isolation in Patients With Atrial Fibrillation: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Background: High-power short-duration (HPSD) ablation has emerged as a promising alternative to conventional power delivery (CPD) for pulmonary vein isolation (PVI) among patients with atrial fibrillation (AF), though its efficacy, procedural efficiency, and safety profile remain uncertain.

Aims: To evaluate and compare the efficacy, procedural efficiency, and safety of HPSD versus CPD ablation strategies for PVI in patients with AF through a systematic review and meta-analysis of randomized controlled trials (RCTs).

Materials And Methods: PubMed, Embase, Cochrane Library, and ClinicalTrials.

Sleep Disruption and Atrial Fibrillation: Evidence, Mechanisms and Clinical Implications.

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia, with its incidence rising due to aging populations, obesity, and advancements in diagnostic modalities. The interplay between sleep disorders and AF is increasingly recognized, with obstructive sleep apnea (OSA) serving as a well-established risk factor. However, emerging evidence implicates additional sleep disturbances-including central sleep apnea, insomnia, and restless legs syndrome-in AF pathogenesis and progression.

Trends in atrial fibrillation-related mortality among adults under 65 years in the USA.

Introduction: Atrial fibrillation (AF) is the most common arrhythmia in the USA, contributing to increased risks of mortality and adverse cardiovascular events. While AF is predominantly seen in older adults, over 20% of cases occur in individuals younger than 65 years.

Methods: We conducted a cross-sectional analysis using de-identified data from the CDC WONDER database, covering all US deaths from 1999 to 2020.

Outcomes following catheter ablation for structural ventricular tachycardia stratified by left ventricular ejection fraction: A retrospective cohort study.

Background: Despite advances in catheter ablation for ventricular tachycardia (VT), patients with lower left ventricular ejection fractions (LVEFs) tend to have worse outcomes. However, there is limited understanding of the periprocedural factors associated with recurrence, and whether LVEF directly influences outcomes.

Objectives: The study sought to evaluate the electrophysiological characteristics and outcomes of patients undergoing VT ablation, stratified by LVEF.

Esophageal-Pericardial Fistula: A Systematic Review of Etiology, Diagnostic Features, Management, and Outcomes.

Background: Esophageal-pericardial fistula (EPF) is rare with an incidence of 0.016%-0.04%.

Association of frailty with outcomes of patients undergoing transvenous lead removal for cardiac implantable electronic device infections in the United States.

Background: Frailty, marked by reduced physiological resilience, is associated with adverse outcomes in patients undergoing various cardiovascular procedures. The rising incidence of cardiac implantable electronic device (CIED) infections necessitate transvenous lead removal (TLR), yet the impact of frailty on TLR outcomes remains unclear.

Objective: The purpose of this study was to evaluate the association between frailty and outcomes in patients undergoing TLR for CIED infections.

Catheter Ablation of Right Ventricular Endocavitary Arrhythmias.

Background: Right ventricular (RV) endocavitary arrhythmias remain poorly characterized.

Objectives: The purpose of this study was to define the clinical presentation, ablation outcomes, and long-term prognosis of RV endocavitary arrhythmias.

Methods: Among 3,873 patients undergoing ventricular arrhythmia ablation between 2013 and 2025, 53 (1.

Pulsed Field Ablation for Atrial Fibrillation in Fontan Palliation.

Introduction: Pulsed-field ablation (PFA) is a novel and effective modality for ablation in patients with atrial fibrillation (AF). Available case reports and small series showed promising results in patients with congenital heart disease. However, PFA ablation in Fontan patients has not been reported yet.

Sex, Race, and Socioeconomic Disparities in the Utilization of Transvenous Lead Removal for Patients Hospitalized With Cardiac Implantable Electronic Device Infections in the United States.

Background: Transvenous lead removal (TLR) is a Class I indication for patients with cardiac implantable electronic device (CIED) infections. However, disparities in the utilization of TLR have not been fully explored, particularly concerning demographic and socioeconomic factors.

Objectives: This study aims to examine whether disparities exist among patients hospitalized for CIED infections with respect to the utilization of TLR, focusing on sex, race, and income characteristics.

Real-World Outcomes of Leadless Pacemaker Implantation After Transvenous Lead Removal for Infected Cardiac Implantable Electronic Devices in the United States.

Leadless pacemakers (LPMs) have emerged as a promising alternative to transvenous systems, particularly in patients requiring transvenous lead removal (TLR) due to cardiac implantable electronic device (CIED) infections. However, real-world outcomes following LPM implantation in this setting remain understudied. Using the National Readmissions Database from 2016 to 2021, we identified 41,058 adult patients who underwent LPM implantation, of whom 3,244 (7.

Cardiac function after catheter ablation of ventricular arrhythmias in patients with arrhythmogenic right ventricular cardiomyopathy.

Aims: Catheter ablation is commonly performed in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) for management of ventricular arrhythmias (VAs). The impact of catheter ablation on cardiac function is unknown. The aim is to assess the impact of catheter ablation for VAs on cardiac function in patients with ARVC.

Long-Term Impact of GLP-1 Receptor Agonists on AF Recurrence After Ablation in Obese Patients.

Background: Obesity is an important risk factor associated with atrial fibrillation (AF). The impact of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) on recurrent AF among patients undergoing catheter ablation is not well described.

Objective: This study aimed to evaluate the effect of GLP-1 RA on the recurrence of AF among obese patients after catheter ablation.

Premature Ventricular Complexes and Nonsustained Ventricular Tachycardia in Cardiac Sarcoidosis.

Background: The prevalence and prognostic significance of frequent premature ventricular complexes (PVCs) and nonsustained ventricular tachycardia (NSVT) in cardiac sarcoidosis (CS), especially in patients with normal or mildly decreased left ventricular function, have not been studied.

Objectives: This study sought to investigate the prognostic value of PVCs and NSVT in patients with CS and normal or mildly decreased left ventricular ejection fraction.

Methods: The authors included 192 patients with definite or probable CS with left ventricular ejection fraction >35% and no previous history of ventricular tachycardia (VT)/ventricular fibrillation (VF) or sudden cardiac death, who underwent up to 48 hours of clinically indicated Holter monitoring.

Bacteremia Caused by Rare NFGNB in the ICU: A Single-center Experience.

Introduction: Amongst the non-fermenting gram-negative bacteria (NFGNB), (.) and predominate the landscape. However, less common NFGNB such as , , , and species, amongst others, are assuming increasing importance.

Investigating the 'Diabetes Paradox' in Takotsubo Cardiomyopathy.

Background: The impact of diabetes mellitus (DM) on outcomes of Takotsubo cardiomyopathy (TC) remains unclear, with conflicting evidence suggesting either protective or harmful effects. This study evaluates the association between DM and in-hospital outcomes in TC patients.

Methods: A retrospective analysis of the National Inpatient Sample database (2016-2019) was conducted to compare in-hospital outcomes in TC patients with and without DM.