Computational fluid dynamics model utilizing proper orthogonal decomposition to assess coronary physiology and wall shear stress.

Background: Percutaneous coronary intervention (PCI) to alleviate symptoms and improve outcomes in patients with symptomatic coronary artery disease. However, conventional assessments like coronary angiography may not fully capture the hemodynamic significance of coronary lesions. This study explores the utility of Proper Orthogonal Decomposition (POD) in elucidating coronary flow dynamics pre- and post-stent placement.

Electrocardiogram changes as predictors for new imaging findings in repeat transthoracic echocardiography.

To determine if electrocardiogram (EKG) findings may be a useful tool to predict changes in repeat transthoracic echocardiogram (TTE). We evaluated patients who underwent TTE during hospitalization and their EKGs, and whether findings differed between studies. Of 229 hospitalized patients who underwent repeat TTE, 183 (80%) were abnormal.

Same-Day Discharge After Left Bundle Area Pacing.

Background: Left bundle area pacing (LBAP) has emerged as an area that appears to be an attractive alternative to other forms of physiological pacing owing to its ease and favorable pacing parameters. Same-day discharge after conventional pacemakers, implantable cardioverter defibrillators, and more recently leadless pacemakers have become routine, especially after the COVID-19 pandemic. With the advent of LBAP, the safety and feasibility of same-day discharge remain unclear.

Impact of Wire Sensor Location on Coronary Physiological Measurement.

Background: The location of the wire sensor to measure fractional flow reserve (FFR) and diastolic pressure ratio (dPR) has not been systematically studied. Therefore, we hypothesize that the coronary physiological measurements will vary with the location of the sensor.

Methods: Fifty-four patients were screened, and 30 consecutive patients were enrolled.

Very low tidal volume, high-frequency ventilation in atrial fibrillation ablation: a systematic review.

Background: Ventilation strategies in atrial fibrillation ablation affect procedure outcomes by influencing catheter stability. Studies have highlighted favorable atrial fibrillation (AF) ablation outcomes with the use of high-frequency jet ventilation (HFJV) which has been shown to improve lesion durability, energy delivery, and tissue contact. However, this mode of ventilation is not readily available.

Clozapine Intoxication in a Patient on Chronic Use With a Short-Term Noncompliance.

Clozapine has been associated with various adverse effects at both subtherapeutic and standard doses. These adverse effects are most commonly seen during the initiation of therapy in treatment-naïve patients. However, reports of intoxication in patients with long-term use of clozapine are yet to be documented.

Staphylococcus Toxin-Mediated Motor Polyneuropathy.

Unlabelled: infection is known to cause a variety of neurologic complications, most involving the CNS, however, rarely have cases of affecting the peripheral nervous system been reported in literature. We report a case of toxin-mediated motor polyneuropathy in a patient presenting with acute flaccid quadriplegia.

Case Summary: A 64-year-old female with mantle cell lymphoma on oral chemotherapy with ibrutinib presents with malaise and progressive ascending bilateral lower extremity weakness.

A Rare Presentation of Cardiac Aspergilloma in an Immunocompetent Host: Case Report and Literature Review.

Cardiac aspergilloma is exceptionally rare with only a handful of cases reported and majority of them being in immunocompromised patients. Here, we present a case of cardiac aspergilloma involving the right and left ventricle in an immunocompetent patient that initially presented with acute limb ischemia. He was later found to have a cardiac mass with histopathological diagnosis confirming Aspergillus species.

Murine Typhus Presenting with Acute Psychosis and Disseminated Intravascular Coagulation: A Case Report.

Murine typhus is an endemic infectious disease caused by Rickettsia typhi and is transmitted by fleas. It typically causes a mild illness with symptoms of fever, rash, headache, chills, and non-specific gastrointestinal complaints. However, there have been no reported cases in the literature of murine typhus infection causing symptoms of acute psychosis and disseminated intravascular coagulation (DIC).