Diagnosis melanoma with artificial intelligence systems: A meta-analysis study and systematic review.

Background: One of the most promising and rapidly advancing research areas in recent years is using dermoscopic images for automatic diagnosis with artificial intelligence and machine learning methods.

Objective: This study aimed to synthesize the existing studies for the clinical use of applications made with artificial intelligence methods and to summarize the predictive performance of deep learning and hybrid models-based algorithms in all these studies with a large-scale meta-analysis.

Method: The literature review was conducted between January 2006 and May 2024, and meta-analysis data were created by scanning the Web of Science (WOS), Scopus and MEDLINE databases.

Dual Benefits of Oral Tranexamic Acid: Reducing Melasma Severity and Inflammation.

Background: Melasma is a chronic hyperpigmentation disorder influenced by hormonal factors, ultraviolet exposure, and inflammation. While oral tranexamic acid (TXA) is an established treatment, its effects on systemic inflammation remain unclear.

Aims: This study aimed to evaluate the impact of TXA on melasma severity and inflammatory markers.

Efficacy, safety, and recurrence in seborrheic dermatitis: A dose-dependent analysis of oral isotretinoin (10 mg vs 20 mg).

Background: This study aimed to compare the efficacy, recurrence rates, and patient-reported satisfaction of 10 mg versus 20 mg daily isotretinoin in individuals with moderate to severe seborrheic dermatitis.

Methods: A retrospective cohort study was conducted on 234 patients treated with 10 mg (n = 126) and 20 mg (n = 108) isotretinoin. Disease severity was assessed using the Seborrheic Dermatitis Area Severity Index (SDASI), while quality of life and treatment satisfaction were evaluated using the Dermatology Life Quality Index (DLQI) and Treatment Satisfaction Questionnaire for Medication 9.

Quality of life, sleep, and psychological well-being in chronic spontaneous urticaria patients receiving omalizumab: a case-control study.

Chronic spontaneous urticaria (CSU) impacts both physical and mental well-being, causing distress and sleep disturbances. While omalizumab reduces disease activity, its effects on mental health and quality of life remain unclear. This study assesses the psychosocial burden and sleep disturbances in CSU patients receiving omalizumab compared to healthy controls and explores their relationship with disease parameters.

Unveiling the effectiveness and safety spectrum of biologic therapies in psoriasis: a three-year real-world analysis.

Background: Psoriasis vulgaris is a chronic immune-mediated inflammatory disease that significantly affects quality of life, particularly in severe cases and anatomically challenging areas. Biologic therapies targeting immune pathways have improved clinical outcomes; however, variability in effectiveness, safety, and drug survival necessitates further investigation.

Objectives: This study aimed to evaluate the effectiveness, safety, and drug survival of biologic therapies in patients with moderate-to-severe psoriasis vulgaris.

Self-Induced Nail Disorders: Clinical and Demographical Features.

Background: Self-induced nail disorders (SINDs) are a subset of body-focused repetitive behaviors (BFRBs) characterized by pathological grooming habits that damage the nail and periungual structures. These disorders were classified into subgroups based on the specific methods individuals use to harm their nails. Despite their prevalence and potential psychological impact, limited data exist.

Efficacy of pro-yellow laser versus cryotherapy in treating cutaneous lesions of Kaposi's sarcoma: a comparative study.

This study aimed to evaluate the efficacy of Pro-Yellow Laser (PYL) in treating plaque and patch lesions of classical Kaposi's Sarcoma (KS) and compare its outcomes with cryotherapy (CT). A single-blind, randomized, comparative experimental study was conducted on nine HIV-negative classical KS patients at Kocaeli University Dermatology Outpatient Clinic between April 2022 and April 2023. Each patient received both CT and PYL treatments on separate lesions.

Systemic Anti-Inflammatory Effects of Isotretinoin: Evaluation of Red Cell Distribution Width to Lymphocyte and Platelet Ratios as New Hematological Markers and Clinical Outcomes in Acne Vulgaris.

Background: Acne vulgaris is a chronic inflammatory skin disease influenced by systemic immune responses. While isotretinoin is the most effective treatment for severe acne, its effects on hematological markers of inflammation, in particular red cell distribution width (RDW)-to-lymphocyte and RDW-to-platelet ratios, remain unclear.

Methods: This retrospective study analyzed 450 acne patients treated with isotretinoin for at least 24 weeks.

Vascular Remodeling in Rosacea: A Study on Microcirculatory Insights Using Oral Capillaroscopy.

Background: Rosacea is a chronic inflammatory skin condition characterized by facial erythema, telangiectasia, and papules. Although clinical assessment is essential for diagnosis, objective criteria for evaluating severity are lacking. This study aimed to investigate the relationship between rosacea severity, disease duration, and associated microvascular changes through oral mucosal capillaroscopy.

Prediction of treatment efficacy in psoriasis vulgaris using dermoscopic and capillaroscopic findings: a prospective cohort study.

Introduction: Psoriasis is a chronic inflammatory skin disorder affecting millions worldwide. Dermoscopy and proximal nailfold capillaroscopy have emerged as valuable tools for understanding the pathophysiology and treatment response of psoriasis lesions.

Objectives: This study aimed to contribute to the limited literature on using dermoscopic findings to detect treatment effectiveness in patients with psoriasis vulgaris.

Social media use as a source of information by acne vulgaris patients.

Background: Social media and internet usage is undeniably high. Misinformation obtained from the internet and wrong treatment methods can cause serious problems in patients with acne vulgaris (AV). In this study, the sociodemographic data of AV patients, their frequency of using the internet as an information source, the relationship between them, and their attitudes and behaviors regarding their disease due to these programs were examined.

The effect of COVID-19 on development of hair and nail disorders: a Turkish multicenter, controlled study.

Background: A broad spectrum of skin diseases, including hair and nails, can be directly or indirectly triggered by COVID-19. It is aimed to examine the type and frequency of hair and nail disorders after COVID-19 infection.

Methods: This is a multicenter study conducted on consecutive 2171 post-COVID-19 patients.

The relationship between hidradenitis suppurativa and irritable bowel syndrome: a cross-sectional study.

Background: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder in which one experiences abdominal pain, tension, cramping, bloating, and changes in the form and frequency of defecation, without an underlying organic disease. Many skin diseases have been reported to be more common in people with functional bowel disease. To our knowledge, however, no previous study investigated the potential relationship between hidradenitis suppurativa (HS) and IBS.