Role of Artificial Intelligence in Reducing Data Deluge From Cardiac Implantable Electronic Devices.

Background: Remote monitoring (RM) is the standard of care for patients with cardiac implantable electronic devices (CIEDs). Data deluge from RM of CIEDs is one of the major challenges being faced by cardiac device clinics.

Objectives: The purpose of this study was to highlight the role of artificial intelligence (AI) in reducing data deluge from CIEDs and to elucidate its performance in augmenting the traditional device clinic workforce.

Simultaneous Endocardial and Epicardial Approach for Successful Closure of Left Atrial Appendage With Difficult Anatomy.

Background: Left atrial appendage closure (LAAC) is increasingly used for stroke prevention; however, left atrial appendage (LAA) anatomy may pose significant challenges.

Case Summary: A 67-year-old man with paroxysmal atrial fibrillation, CHADS-VASc Score of 3, and recurrent falls was referred for LAAC. Owing to challenging anatomy noted during preoperative imaging, epicardial access was obtained at procedure onset.

Current Safety Profile of Pulse Field Ablation: Not Everything that Shines Is Gold.

Pulse field ablation is a novel, non-thermal alternative for catheter ablation of atrial fibrillation. Preclinical and early clinical studies have demonstrated a favorable safety profile with significant reductions in esophageal and pulmonary vein injury compared to radiofrequency ablation. However, there are still procedural and energy-related complications inherent to electroporation, tissue selectivity, and energy-dosing.

NEMESIS-PFA: Investigating Collateral Tissue Injury Associated With Pulsed Field Ablation.

Background: Early evidence showed reduced complications with pulsed field ablation (PFA), but non-target tissue collateral damage created by electroporation effects is poorly understood and may significantly differ between systems.

Objectives: In this study, the authors evaluated the collateral effects of PFA.

Methods: NEMESIS-PFA is a multicenter, observational registry of patients who underwent AF ablation from March 2024 onwards with any approved PFA systems-either a circular multielectrode array, spherical, pentaspline, or variable loop catheter-or radiofrequency ablation (RFA).

Impact of Artificial Intelligence-Enhanced Insertable Cardiac Monitors on Device Clinic Workflow and Resource Utilization.

Background: Insertable cardiac monitors (ICMs) are essential for managing arrhythmias but often generate large numbers of transmissions and false alerts. Integrating artificial intelligence (AI) as part of the ICM workflow can reduce this burden. However, its impact on clinic workflow and resource utilization must be better understood.

Pilot Study of Early Catheter Ablation and Neurological Outcomes in Atrial Fibrillation-Related Stroke: RESCUE-STROKE.

Background: Inadequate management of atrial fibrillation (AF) after stroke is associated with a worse prognosis, and the impact of early rhythm control with catheter ablation (CA) on neurological outcomes in these patients is poorly understood.

Objectives: This study sought to evaluate the impact of early rhythm control with CA in patients with new-onset AF at the time of stroke.

Methods: We performed a retrospective, observational study of patients hospitalized with stroke and new-onset AF from 2021 to 2023.

Epidemiology of Atrial Fibrillation in Heart Failure.

Atrial fibrillation and heart failure are common cardiovascular conditions that are intricately linked to each other, with a significant impact on morbidity, mortality, and quality of life. These two conditions can create a vicious pathophysiologic milieu associated with neurohormonal changes, elevated cardiac filling pressure, myocardial remodeling, systemic and regional inflammation, fibrosis, and diminished myocardial contractility. It is well known that cardiomyopathy can cause atrial fibrillation and vice-versa, but often it is difficult to sort which came first.

Dynamic data-driven management of atrial fibrillation with implantable cardiac monitors: The MONITOR AF study.

Background: Implantable cardiac monitors (ICMs) provide valuable insights into managing atrial fibrillation (AF). Data suggest that ICMs increase AF detection, but their impact on management is still uncertain.

Objective: We aimed to evaluate and to compare the impact of ICMs on the clinical management of AF.

Are high school cardiopulmonary resuscitation education mandates working? Insights from a high school survey on CPR knowledge, attitudes, and readiness.

Background: The use of cardiopulmonary resuscitation (CPR) and automated external defibrillators (AEDs) significantly improve the chances of survival after out-of-hospital cardiac arrest. Subsequently, state laws mandate training in CPR and AED use for high school graduation. However, training and its impact vary and must be better understood.

Feasibility, safety, and efficacy of a novel external compression vascular closure device: The LockeT® study.

Introduction: Hemostasis following large-bore femoral vein access remains a challenge. Manual compression has been the standard of care but requires bedside staff, prolonged bed rest, and longer length of stay. The LockeT is an external compression device that attempts to address these issues while achieving venous hemostasis.

Atrial fibrillation ablation in heart failure patients: Where do we stand in 2023? - State of the art review.

Atrial fibrillation (AF) and heart failure are common overlapping cardiovascular disorders. Despite important therapeutic advances over the past several decades, controversy persists about whether a rate control or rhythm control approach constitutes the best option in this population. There is also considerable debate about whether antiarrhythmic drug therapy or ablation is the best approach when rhythm control is pursued.

Update on the Practical Role of Echocardiography in Selection, Implantation, and Management of Patients Requiring Left Ventricular Assist Device Therapy.

Purpose Of Review: Echocardiography is a valuable tool for management of patients with a left ventricular assist device (LVAD). We present an updated review on the practical applications of the role of echocardiography for pre- and postoperative evaluation of patients selected.

Recent Findings: The LVAD is a temporary or permanent option for patients with advanced heart failure who are unresponsive to other therapy.

Endovascular Treatment of Right Heart Masses Utilizing the AngioVac System: A 6-Year Single-Center Observational Study.

Objective: To describe our institution's experience with the AngioVac system.

Background: Intracardiac and intravascular masses previously required surgical excision, but now, there are a number of minimally invasive options. With the advent of vacuum aspiration, more specifically the AngioVac System (AngioDynamics, NY, USA), there exists a system with both low mortality and minor complications.

Early toxicity and clinical outcomes after chimeric antigen receptor T-cell (CAR-T) therapy for lymphoma.

Background: Chimeric antigen receptor T-cell (CAR-T) infusion is associated with early toxicity. Yet, whether early toxicity development holds ramifications for long-term outcomes is unknown.

Methods: From a large cohort of consecutive adult patients treated with CAR-T therapies for relapsed or refractory lymphomas from 2016 to 2019, we assessed progression-free survival (PFS), by toxicity development (cytokine release syndrome (CRS), neurotoxicity, or cardiotoxicity].