Comparative Analysis of Single-Dose and Multiple-Dose Antibiotic Prophylaxis in Preventing Surgical Site Infections.

Background: Surgical site infections (SSIs) represent a significant challenge following general surgical procedures, affecting approximately 1 in 24 patients undergoing inpatient surgery in the United States. Despite advances in antibiotic therapies and antiseptic techniques, SSIs continue to impact surgical outcomes. Effective prophylactic antibiotic administration is critical for reducing SSI rates.

Evaluation of Inflammatory Markers and Clinical Outcomes in Patients with Acute Pancreatitis: A Prospective Cohort Study.

Background: Acute pancreatitis (AP) is a sudden inflammatory process of the pancreas that can lead to varying degrees of severity, ranging from mild discomfort to life-threatening conditions. Identifying key inflammatory markers at an early stage is crucial to predicting clinical outcomes and improving management.

Objective: This study aims to evaluate the association between inflammatory markers-C-reactive protein (CRP), serum amylase, and white blood cell (WBC) count-and clinical outcomes in patients with acute pancreatitis.

Plant extracts with antioxidant and hepatoprotective benefits for liver health: A bibliometric analysis of drug delivery systems.

Background: The rising global burden of liver diseases, such as non-alcoholic fatty liver disease and liver fibrosis, has necessitated innovative therapeutic approaches. Plant-based therapies, recognized for their anti-inflammatory and antioxidant properties, have shown promising effects. However, poor bioavailability limits their clinical application.

Scale selection and machine learning based cell segmentation and tracking in time lapse microscopy.

Monitoring and tracking of cell motion is a key component for understanding disease mechanisms and evaluating the effects of treatments. Time-lapse optical microscopy has been commonly employed for studying cell cycle phases. However, usual manual cell tracking is very time consuming and has poor reproducibility.