Treatment compliance and results of exposure in vivo for patients with musculoskeletal pain after implementation in a rehabilitation center: a series of single case studies.

Purpose: A subgroup of chronic musculoskeletal pain patients experiences pain-related fear, for which exposure (EIV) has been developed. While EIV has shown effectiveness in research settings, its implementation in clinical practice remains limited. The purpose of this study was to assess the results and procedural fidelity directly following implementation in a clinical setting.

First-Trimester Fetal Cardiac Function Measurements Using Spatio-Temporal Image Correlation and Two Ultrasound-Related Post-Processing Methods: A Feasibility and Reproducibility Study.

Objective: To study the feasibility and reproducibility of two ultrasound (US) related post-processing methods for first-trimester fetal cardiac function assessment by ventricle volume measurements.

Method: First-trimester transvaginal Spatio-Temporal Image Correlation (STIC) US datasets acquired between 11-13 weeks gestational age (GA) were used to perform fetal cardiac ventricle volume (FCVV) measurements in the end-diastolic (EDVV) and end-systolic (ESVV) phases using two methods: the manual segmentation method Virtual Organ Computed-Aided AnaLysis (VOCAL) and (semi-)automated volume measuring method Virtual Reality (VR). Reproducibility was assessed by calculating the intra-, interobserver and intersystem agreement using intraclass correlation coefficients (ICCs) followed by Bland-Altman plots.

Apollo: a comprehensive GPU-powered within-host simulator for viral evolution and infection dynamics across population, tissue, and cell.

Modern sequencing instruments bring unprecedented opportunity to study within-host viral evolution in conjunction with viral transmissions between hosts. However, no computational simulators are available to assist the characterization of within-host dynamics. This limits our ability to interpret epidemiological predictions incorporating within-host evolution and to validate computational inference tools.

An overview and evaluation of first-trimester physiological fetal human anatomy using 3-dimensional ultrasound combined with virtual reality techniques.

Study Question: What (physiological) first-trimester fetal anatomic structures can be discerned by ultrasound (US) and can these structures be visualized using 3-dimensional (3D) US combined with virtual reality (VR) in a prospective clinical setting?

Summary Answer: 3D US combined with VR techniques has shown to be applicable for the assessment of fetal anatomy in the first trimester and may serve as a valuable tool for both professional training and patient counseling.

What Is Known Already: Due to technological developments, new imaging modalities are becoming available and the visualization of fetal anatomic structures continues to improve. Consequently, in recent years, the focus of antenatal US screening has progressively shifted toward the first trimester of pregnancy.