Proof of Concept of an Integrated Laser Irradiation and Thermal/Visible Imaging System for Optimized Photothermal Therapy in Skin Cancer.

Laser energy is widely used as a selective photothermal heating agent in cancer treatment, standing out for not relying on ionizing radiation. However, in vivo tests have highlighted the need to develop irradiation techniques that allow precise control over the illuminated area, adapting it to the tumor size to further minimize damage to surrounding healthy tissue. To address this challenge, a proof of concept based on a laser irradiation system has been designed, enabling control over energy, exposure time, and irradiated area, using galvanometric mirrors.

Aptamer-Based Microfluidic Assay for In-Field Detection of Salicylic Acid in -Infected Strawberries.

Rapid detection of plant infections is crucial for minimising crop loss and optimising management strategies, particularly in the context of climate change. While traditional diagnostic methods provide precise measurements of phytohormones such as salicylic acid (SA), a key regulator of plant defence responses, their reliance on bulky equipment and lengthy analysis times limits field applicability. This study presents a microfluidic-based aptamer assay for SA detection, enabling rapid and sensitive fluorescence-based readout from plant samples.

Multi-technique computational assessment of fluoride uptake in enamel using PIGE, NEXAFS, and Raman spectroscopy.

The uptake of fluoride in the enamel matrix is an effective strategy to prevent demineralization and caries formation. In this study a comprehensive methodology is developed to evaluate and understand the uptake of fluoride in human enamel. Twenty-six healthy anterior teeth were sectioned in half; one half remained untreated, while the other was treated with 50 mg mL NaF (equivalent to 22.

Phase transformation in lead titanate based relaxor ferroelectrics with ultra-high strain.

The reverse piezoelectric effect allows for the conversion of an electrical input signal into mechanical displacement and forms the basis for the operation of positioners and actuators. Addressing the practical need for cost-effective sensitive materials, we introduce erbium-doped lead magnesium niobium titanate ceramics which exhibit exceptionally high strain (3.19% bipolar and 0.

A Reusable Capillary Flow-Driven Microfluidic System for Abscisic Acid Detection Using a Competitive Immunoassay.

Point-of-care (PoC) devices offer a promising solution for fast, portable, and easy-to-use diagnostics. These characteristics are particularly relevant in agrifood fields like viticulture where the early detection of plant stresses is crucial to crop yield. Microfluidics, with its low reagent volume requirements, is well-suited for such applications.