1 results match your criteria: "Slovakia. anna.kalosi@savba.sk and Centre for Advanced Material Application[Affiliation]"
A bioconjugated MoS based nanoplatform with increased binding efficiency to cancer cells.
Biomater Sci
March 2020
Department of Multilayers and Nanostructures, Institute of Physics, Slovak Academy of Sciences, Dúbravská cesta 9, 845 11 Bratislava, Slovakia. and Centre for Advanced Material Application, Slovak Academy of Sciences, Dúbravská cesta 9, 845 11 Bratislava, Slovakia.
We evaluate the application of surfactant-free liquid-phase exfoliated MoS2 nanosheets as a nanoplatform for a cancer detection and treatment system equipped with an antibody-antigen based recognition element. Employing antigen-antibody binding, we increased the probability of the endocytosis of MoS2 nanosheets into CAIX expressing cells by 30%. The nanosheets are functionalized with a specific antibody M75, which forms an antigen-antibody complex with CAIX.
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