Do we know more about the mechanobiology of the intervertebral disc in space than on Earth?

This work provides a perspective on the loading protocols used in whole-organ interverterbal disc culture studies using bioreactors. We put this in the context of in vivo spinal loading, and we put forward the case that the majority of previous bioreactor studies have more in common with spinal loading in space than on Earth. Finally, we provide an outlook for the future of bioreactor research, to provide data more relevant to spinal loading on Earth, and maximize the translational potential of findings to the clinical setting.

Rapid, repeatable landscape-scale mapping of tree, hedgerow, and woodland habitats (THaW), using airborne LiDAR and spaceborne SAR data.

In the UK, tree, hedgerow, and woodland (THaW) habitats are key havens for biodiversity and support many related ecosystem services. The UK is entering a period of agricultural policy realignment with respect to natural capital and climate change, meaning that now is a critical time to evaluate the distribution, resilience, and dynamics of THaW habitats. The fine-grained nature of habitats like hedgerows necessitates mapping of these features at relatively fine spatial resolution-and freely available public archives of airborne laser scanning (LiDAR) data at <2 m spatial resolution offer a means of doing so within UK settings.

Exploring the effect of case management in homelessness per components: A systematic review of effectiveness and implementation, with meta-analysis and thematic synthesis.

Background: Adequate housing is a basic human right. The many millions of people experiencing homelessness (PEH) have a lower life expectancy and more physical and mental health problems. Practical and effective interventions to provide appropriate housing are a public health priority.