55 results match your criteria: "Networking Research Centre on Bioengineering[Affiliation]"
Extraperitoneal and intraperitoneal behavior of several biological meshes currently used to repair abdominal wall defects.
J Biomed Mater Res B Appl Biomater
February 2015
Department of Medicine and Medical Specialties, Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Faculty of Medicine and Health Sciences, University of Alcalá, Madrid, Spain.
This study compares the behavior of several cross- and noncrosslinked biomeshes (Permacol®, CollaMend®, Surgisis®, Tutomesh®, and Strattice®) currently used for abdominal wall repair when implanted intraperitoneally and extraperitoneally. Material and Methods. Intraperitoneal (IP) implants were fixed on the parietal peritoneum and partial abdominal wall defects (EP) were repaired using each of the biomeshes, in the rabbit abdominal wall.
View Article and Find Full Text PDFVariable-temperature size exclusion chromatography for the study of the structural changes in g-quadruplex.
ISRN Biochem
May 2015
Solution Equilibria and Chemometrics Group (Associate Unit UB-CSIC), Department of Analytical Chemistry, University of Barcelona, Diagonal 647, 08028 Barcelona, Spain.
Article Synopsis
- This study examines the structural variations of a guanine-rich DNA sequence linked to the human c-kit oncogene using techniques like circular dichroism spectroscopy and size exclusion chromatography.
- The original sequence, ckit21, is found to exist as a blend of single and multiple G-quadruplex structures.
- Mutations can change the structure from parallel to antiparallel G-quadruplexes and eliminate multimeric forms, with temperature also affecting these conformations as observed in CD and SEC results.
Improvement of cognitive flexibility and cingulate blood flow correlates after atypical antipsychotic treatment in drug-naive patients with first-episode schizophrenia.
Psychiatry Res
December 2011
Department of Mental Health, Hospital de Terrassa-Consorci Sanitari de Terrassa, Terrassa, Spain.
The aim of this study was to examine the changes in cognitive flexibility and associated cerebral blood flow in the anterior cingulate lobe of drug-naive patients with first-episode schizophrenia who were treated with atypical antipsychotics for 6 weeks. Single photon emission computed tomography (SPECT) images were obtained from 8 healthy subjects both at rest and while performing the flexibility subtest of the TAP (Test for Attentional Performance). SPECT images were obtained in parallel from 8 first-episode drug-naive schizophrenic patients while they were performing the same task both before and after 6 weeks of neuroleptic treatment.
View Article and Find Full Text PDFPostimplant intraperitoneal behavior of collagen-based meshes followed by laparoscopy.
Surg Endosc
January 2012
Department of Surgery, Faculty of Medicine, University of Alcalá, Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), Alcalá de Henares, Ctra. Madrid-Barcelona, Km 33,600, 28871, Madrid, Spain.
Background: When repairing an abdominal wall defect, sometimes a prosthetic mesh needs to be placed directly on the parietal peritoneum. Although the standard mesh for this purpose is the laminar implant expanded polytetrafluoroethylene (PTFE), it is gradually being replaced by the laminar collagen-based meshes. This study was designed to assess the intraperitoneal behavior of three of these biomeshes, mainly in terms of their susceptibility to adhesion formation.
View Article and Find Full Text PDFSolid lipid nanoparticles as potential tools for gene therapy: in vivo protein expression after intravenous administration.
Int J Pharm
January 2010
Networking Research Centre on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, SLFPB-EHU, Vitoria-Gasteiz, Spain.
Naked plasmid DNA is a powerful tool for gene therapy, but it is rapidly eliminated from the circulation after intravenous administration. Therefore, the development of optimized DNA delivery systems is necessary for its successful clinical use. Solid lipid nanoparticles (SLNs) have demonstrated transfection capacity in vitro, but their application for gene delivery has not been conveniently investigated in vivo.
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