2 results match your criteria: "National Reference center for Hepatitis B and C in Blood Transfusion[Affiliation]"
Variable capacity of 13 hepatitis B virus surface antigen assays for the detection of HBsAg mutants in blood samples.
J Clin Virol
April 2012
National Reference center for Hepatitis B and C in Blood Transfusion, Institut National de la Transfusion Sanguine, Paris, France.
Background: Natural variation and mutations in the envelope protein (S) of hepatitis B virus can translate into HBsAg variants no longer detectable by conventional HBsAg assays.
Objectives: The aim of the study was to assess the performance of 13 commercial assays currently used for screening and clinical analysis of HBsAg variants.
Study Design: The limit of detection (LOD) for each assay was established using two reference standards (WHO HBsAg 00/588 and the SFTS French reference).
Overestimation of incidence of hepatitis B virus mixed-genotype infections by use of the new line probe INNO-LiPA genotyping assay.
J Clin Microbiol
March 2011
National Reference Center for Hepatitis B and C in Blood Transfusion, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France.
The new version of the INNO-LiPA HBV genotyping assay (Innogenetics) developed to identify all hepatitis B virus (HBV) genotypes, A to H, has been evaluated in comparison with sequencing of PCR-amplified HBV DNA from 200 samples before or after cloning. The genotyping data obtained with INNO-LiPA were in agreement with those from direct sequencing in the 179 samples characterized by the two methods. INNO-LiPA revealed 28 mixed infections.
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