4 results match your criteria: "Magee-Womens Research Institute and Foundation and Hillman Cancer[Affiliation]"
All-cause mortality and neighborhood social vulnerability among women with ovarian cancer.
Gynecol Oncol
April 2025
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee-Womens Research Institute and Foundation, Pittsburgh, PA, United States of America; Women's Cancer Research Center, Magee-Womens Research Institute and Foundation and Hillman Cancer
Objective: Neighborhood-level social determinants of health (N-SDoH) impact cancer survival. However, the relationship between N-SDoH and epithelial ovarian cancer (EOC) survival remains understudied.
Methods: We used data on all Pennsylvania residents diagnosed with EOC from 2000 to 2023 throughout the University of Pittsburgh Medical Center to assess the impact of N-SDoH on survival.
Association of neighborhood social vulnerability with ovarian cancer survival.
Gynecol Oncol
January 2025
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee-Womens Research Institute and Foundation, Pittsburgh, PA, United States of America; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh
Objective: Social determinants of health (SDOH) impact cancer outcomes. The CDC Social Vulnerability Index (SVI) integrates scores for four neighborhood-based SDOH domains (socioeconomic status, household characteristics, minority status, and housing type/transportation) to assess neighborhood social vulnerability (NSV). While NSV has been associated with overall cancer mortality and lung, breast, colon, and endometrial cancer-specific mortality, the relationship between NSV as defined by the SVI and ovarian cancer outcomes remains unknown.
View Article and Find Full Text PDFVariables Affecting CA15.3 Tumor Antigen Expression and Antibodies against It in Female National Health and Nutritional Survey Participants.
Cancer Epidemiol Biomarkers Prev
September 2024
Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Background: Cancers of ductal origin often express glycoprotein mucin 1 (MUC1), also known as CA15.3, with higher levels leading to poor prognosis. Conversely, anti-MUC1 antibodies develop in some patients, leading to better prognosis.
View Article and Find Full Text PDFAssociation of allostatic load with overall survival in epithelial ovarian cancer.
Gynecol Oncol
July 2024
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh School of Medicine and Magee-Womens Research Institute and Foundation, Pittsburgh, PA, United States of America; Department of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh
Article Synopsis
- Elevated allostatic load (AL), which reflects cumulative physiological stress, is linked to increased mortality in various cancer patients, but its connection to ovarian cancer mortality was previously unknown.
- This study analyzed data from 201 ovarian cancer patients to examine the relationship between high allostatic load and overall survival, using a robust statistical model to assess outcomes.
- Results indicated that high allostatic load significantly correlated with increased mortality risk in ovarian cancer patients, suggesting it could be a useful marker for identifying those in need of additional socioenvironmental support during treatment.