1 results match your criteria: "India. lalitha253@periyaruniversity.ac.in.[Affiliation]"
TFAA mediated one-pot synthesis of chiral -protected amino acid-derived 1,2,4-oxadiazoles and their antibacterial studies.
Org Biomol Chem
January 2025
Department of Chemistry, Periyar University, Salem-636011, Tamil Nadu, India.
Article Synopsis
- A new one-pot method was developed for creating chiral -protected amino acid substituted 1,2,4-oxadiazoles using hydroxyl amidine and a specific anhydride, promoting sustainability.
- This simple process does not require catalysts, making it a more efficient way to synthesize these amino acids.
- The newly synthesized compounds were tested for antibacterial activity, with one compound (4al) showing notable effectiveness against certain harmful bacteria at a minimal inhibitory concentration of 0.19 μg/mL.