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Polystyrene-bound AlCl - a catalyst for the solvent-free synthesis of aryl-substituted tetrazoles.
Catal Sci Technol
March 2025
Institute of Physical and Theoretical Chemistry, Graz University of Technology Stremayrgasse 9 8010 Graz Austria
Tetrazole moieties are components of various pharmacologically active molecules. Several synthetic protocols for the synthesis of tetrazoles have been developed. Among those, the reaction of organic nitriles with azides catalyzed by Lewis acids (LAs) provides a convenient access.
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