1 results match your criteria: "Center for Research in Atomistic Simulations[Affiliation]"
Insights into the binding of Phenyltiocarbamide (PTC) agonist to its target human TAS2R38 bitter receptor.
PLoS One
August 2010
Statistical and Biological Physics, International School for Advanced Studies and DEMOCRITOS Modeling, Center for Research in Atomistic Simulations, Trieste, Italy.
Humans' bitter taste perception is mediated by the hTAS2R subfamily of the G protein-coupled membrane receptors (GPCRs). Structural information on these receptors is currently limited. Here we identify residues involved in the binding of phenylthiocarbamide (PTC) and in receptor activation in one of the most widely studied hTAS2Rs (hTAS2R38) by means of structural bioinformatics and molecular docking.
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