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J Educ Health Promot
July 2025
Faculty of Health, York University, Toronto.
Background: Despite the benefits of cardiac rehabilitation (CR), women are under-represented, especially in lower-income settings. Technology may be leveraged to tailor CR to better engage women, but this has never been tested in a middle-income country. This study assessed the implementability, usability, engagement, and acceptability of Technology-bAsed Cardiac rehabilitation Therapy (TaCT) in women with cardiovascular disease (CVD) in a middle-income country.
View Article and Find Full Text PDFACS Omega
August 2025
Laboratoire Matériaux Avancés et Phénomènes Quantiques, Faculté des Sciences de Tunis, Université de Tunis El Manar, Campus Universitaire, Tunis 2092, Tunisia.
This paper reports the use of P18-8, a novel conjugated polymer combining poly-(1,4-phenylene-ethynylene) and poly-(1,4-phenylene-vinylene), in the fabrication of an organic diode with the structure ITO/PEDOT:PSS/P18-8/LiF/Al. The electrical properties of the fabricated device were characterized using impedance spectroscopy across a frequency range of 100 Hz to 1 MHz at various applied voltages. The current density-voltage (-) characteristic exhibited ohmic behavior at low applied voltages, while at higher voltages, it conformed to the space charge limited current (SCLC) theory.
View Article and Find Full Text PDFInt J Mol Sci
August 2025
Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal.
Human mitochondrial DNA (mtDNA) is a relevant marker in evolutionary and population genetics, including ancient DNA (aDNA) research, due to inherent characteristics. However, aDNA is prone to damage and sequencing artefacts, potentially confounding evolutionary interpretations. To assess evolutionary patterns in ancient and modern mtDNA, we built a phylogeny comprising 63,965 modern and 3757 ancient public mitogenomes, classified mutations by genomic region and functional effect, and analysed distribution, frequency, and predicted pathogenicity of private and pre-terminal mutations, investigating purifying selection.
View Article and Find Full Text PDFFront Oncol
August 2025
Ajmera Transplant Centre, University Health Network, Toronto, ON, Canada.
Hepatocellular carcinoma (HCC) is a highly lethal, aggressive malignancy. Little is known about the evolutionary trajectories of HCC and how clinical decision-making could be informed based on biopsies of the initial tumour. Here, we report the whole-exome sequencing of a unique series of resected HCC tumours and matched recurrences.
View Article and Find Full Text PDFMagn Reson Imaging
November 2025
Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany; Department of Radiology and Neuroradiology, Section Biomedical Physics, Dortmund Clinical Centre gGmbH, Dortmund, Germany; Department of Radiology and Neuroradiology, Dortmund Clinical Centre gG
Background: Susceptibility-weighted imaging (SWI) is a promising MRI technique for localizing and characterizing intramammary calcifications. However, no clinically established breast SWI protocol currently exists, and susceptibility effects caused by breast calcifications remain insufficiently studied due to a lack of realistic imaging phantoms and validated simulation models. This study aimed to systematically investigate magnetic susceptibility effects both in silico and in vitro, considering various sizes and shapes of calcifications using in vivo imaging protocol parameters.
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