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Despite growing recognition of the interdependencies of resilience across systems, sectors, and levels (SSLs), translating this understanding into coordinated action remains a challenge. This study identifies seven systemic gaps that reinforce a persistent know–do gap, creating an unhealthy that reinforces fragmentation across SSLs. In response, seven prerequisites for synergizing resilience are proposed, along with a working definition of Synergistic Resilience.To operationalize this concept, the Synergistic Resilience Compass (SRC) is introduced—a structured, adaptable, and practitioner-focused framework. A Seven-Step Rollout is proposed to guide implementation across diverse contexts, while illustrating SRC’s utility through case vignettes.Benefits, along with practice and research implications of SRC, are discussed through potential use case examples, balancing constructivism and pragmatism. Limitations and future directions, including iterative refinement, toolkit development, and creating a community of practice, are highlighted. The SRC provides a framework for synergizing resilience across SSLs where 1+1 becomes 3.
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http://dx.doi.org/10.1017/dmp.2025.10185 | DOI Listing |
Disaster Med Public Health Prep
September 2025
Department of Global Health, https://ror.org/00cvxb145University of Washington, Seattle, Washington, USA.
Despite growing recognition of the interdependencies of resilience across systems, sectors, and levels (SSLs), translating this understanding into coordinated action remains a challenge. This study identifies seven systemic gaps that reinforce a persistent know–do gap, creating an unhealthy that reinforces fragmentation across SSLs. In response, seven prerequisites for synergizing resilience are proposed, along with a working definition of Synergistic Resilience.
View Article and Find Full Text PDFKorean J Clin Oncol
August 2025
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Cancer immunotherapy represents a transformative strategy in modern oncology, utilizing the body's immune system to recognize and eliminate malignant cells with precision. Unlike traditional therapies, which often directly target the tumor, immunotherapy enhances the immune system's inherent ability to differentiate between healthy and cancerous cells. The advent of immune checkpoint inhibitors (ICIs), particularly those targeting the PD-1/PD-L1 and CTLA-4 pathways, has marked a significant breakthrough in this field.
View Article and Find Full Text PDFPolymers (Basel)
August 2025
Petroleum Engineering Department, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Malaysia.
Maximizing hydrocarbon recovery from mature and complex reservoirs is constrained by heterogeneity, sand production, and harsh operational conditions. While polyacrylamide (PAM)-based systems are pivotal in addressing these challenges, a comprehensive synthesis of their transformative evolution and multifunctional capabilities remains overdue. This review critically analyzes advancements in PAM-based materials for enhanced oil recovery (EOR), conformance control, and sand management.
View Article and Find Full Text PDFFoods
August 2025
College of Food Science, Southwest University, Chongqing 400715, China.
Lytic polysaccharide monooxygenases (LPMOs) represent copper-dependent enzymes pivotal in breaking down resilient polysaccharides like cellulose and chitin by means of oxidation, creating more accessible sites for glycoside hydrolases. To elevate the conversion efficiency of chitin, an AA10 LPMO was identified from the genome of 2-40 and heterologously expressed. The optimal pH for the activity of recombinant LPMO10A is 9.
View Article and Find Full Text PDFJ Genet Eng Biotechnol
September 2025
Key Laboratory of Biology and Genetic Improvement of Oil Crops, Ministry of Agriculture, Oil Crops Research Institute of the Chinese Academy of Agricultural Sciences (CAAS), Wuhan 430062, China; National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya 572024, China
Peanut (Arachis hypogaea L.) cultivation is increasingly vulnerable to climate change, with drought and heat stress emerging as major constraints to productivity and food security. This review explores the critical role of root architecture in enhancing peanut adaptation to environmental stressors, and evaluates current strategies and future directions for improving root traits through genetic, physiological, and agronomic approaches.
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