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http://dx.doi.org/10.1245/s10434-025-18282-w | DOI Listing |
Ann Surg Oncol
September 2025
Department of Dermatology, Oregon Health and Science University, Portland, OR, USA.
Front Neurol
July 2024
Department of Speech, Language, and Hearing Sciences and Dalton Cardiovascular Center, University of Missouri, Columbia, MO, United States.
Introduction: Aspiration pneumonia, a leading cause of mortality, poses an urgent challenge in contemporary society. Neuromuscular electrical stimulation (NMES) has been commonly used in dysphagia rehabilitation. However, given that NMES at motor threshold targets only specific muscles, it carries a potential risk of further compromising functions related to swallowing, respiration, and airway protection.
View Article and Find Full Text PDFJ Appl Physiol (1985)
April 2024
Department of Speech, Language, and Hearing Sciences and Dalton Cardiovascular Center, University of Missouri, Columbia, Missouri, United States.
Opioids are well-known to cause respiratory depression, but despite clinical evidence of dysphagia, the effects of opioids on swallow excitability and motor pattern are unknown. We tested the effects of the clinically relevant opioid buprenorphine on pharyngeal swallow and respiratory drive in male and female rats. We also evaluated the utility of 5-HT agonists (8-OH-DPAT and buspirone) to improve swallowing and breathing following buprenorphine administration.
View Article and Find Full Text PDF