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Division of Population Health Research, Division of Intramural Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland, United States.
This study aimed to explore associations between self-reported first-trimester vaginal bleeding status and fetal body composition and organ volumes measured by three-dimensional (3D) ultrasound across pregnancy.The NICHD Fetal 3D Study (2015-2019) included individuals with singleton pregnancies at low risk for fetal growth abnormalities ( = 2,634). Fetal body composition measures of arm, abdomen, and thigh, and organ volumes including cerebellum, lung, kidney, and liver, were measured up to five times between 15 and 40 weeks using 3D ultrasound.
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We report 2 cases of fetal total anomalous pulmonary venous drainage (TAPVD) diagnosed in subsequent pregnancies in the same patient. In the first pregnancy, supracardiac TAPVD with obstruction at the ascending vein was identified at 20 weeks. Three-dimensional (3D) motion-corrected fetal cardiac magnetic resonance imaging (MRI) aided visualization of the venous pathway and revealed subtle T2-weighted lung heterogeneity, suggesting secondary pulmonary lymphangiectasia.
View Article and Find Full Text PDFReference charts for first-trimester placental volume derived using OxNNet.
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Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Objective: To establish a comprehensive reference range for OxNNet-derived first-trimester placental volume (FTPV), based on values observed in healthy pregnancies.
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