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Unilateral cleft lip repair methods have evolved from straight-line repairs to geometric procedures, rotation-advancement, and contemporary hybrid techniques. The Fisher anatomical subunit repair is a versatile, effective, and highly reproducible technique. It utilizes mathematical precision in design, avoids multi-point closure, minimizes scar burden, and does not compromise horizontal lip length for vertical height in various deformities. Despite these benefits, the repair has been criticized for its complexity. We describe a five-step distillation of the repair intended to clarify the procedure and provide adoptees an entry point to the benefits of the technique.
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http://dx.doi.org/10.1097/PRS.0000000000012435 | DOI Listing |
Unilateral cleft lip repair methods have evolved from straight-line repairs to geometric procedures, rotation-advancement, and contemporary hybrid techniques. The Fisher anatomical subunit repair is a versatile, effective, and highly reproducible technique. It utilizes mathematical precision in design, avoids multi-point closure, minimizes scar burden, and does not compromise horizontal lip length for vertical height in various deformities.
View Article and Find Full Text PDFJ Thorac Oncol
July 2025
Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.
Introduction: TNM staging systems create prognostic categories by anatomic extent of disease. Whether therapeutically important molecular alterations in NSCLC augment the prognostic information of TNM staging is unclear. To study this, we analyzed molecular data from the ninth edition of the lung cancer staging system.
View Article and Find Full Text PDFJ Esthet Restor Dent
September 2025
Department of Prosthodontics, Seoul National University School of Dentistry, Seoul, Republic of Korea.
Objective: To evaluate the impact of occlusion type and artificial intelligence-based computer-aided design (CAD) software on the geometric accuracy and clinical quality of auto-generated anterior and posterior crown designs.
Methods: Five typodont models representing various occlusion types (normal, Class I anterior diastema, Class II division 1, Class II division 2, and Class III anterior crossbite occlusion) underwent crown preparation for the maxillary right central incisor and first molar. Ten sets of intraoral scans were obtained from each prepared model, and crown designs were automatically generated using two software programs: deep learning-based (DL; Dentbird) and conventional automated (CA; Auto Workflow, 3Shape) (n = 10).
Ann Clin Transl Neurol
September 2025
Brain & Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
Objective: Chronic pain is prevalent among people living with Parkinson's disease (PD). We analyzed data from 10,631 Australian individuals with PD to assess the prevalence, age and sex differences, severity, anatomical distribution, clinical history, and associated factors.
Methods: We analysed data from 10,631 participants with PD enrolled in the Australian Parkinson's Genetics Study (APGS), an ongoing nationwide cohort.
JACC Case Rep
August 2025
Division of Cardiology, Department of Medicine, Johns Hopkins Hospital School of Medicine, Baltimore, Maryland, USA; Division of Pediatric Cardiology, Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Background: Coronary artery fistulas (CAFs) are rare anomalies that can cause ischemia, arrhythmias, and sudden cardiac death. Conventional closure techniques often fail in anatomically complex cases.
Summary: We present the first-in-human use of a customized, partially covered G-Armor pulmonary artery (PA) stent to manage a left main-to-right pulmonary artery fistula in a patient with Shone complex.