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We developed and implemented a PrEP navigation program ("SNAPS") in a NYC safety-net hospital with the objectives to co-locate navigation, clinical PrEP services, and payment assistance. Adherence and retention to PrEP-related care were assessed by mean medication possession ratios (MPRs) and number of appointments over 12 months. Compared to the pre-SNAPS cohort, the post-SNAPS cohort was less likely to be cisgender male (64.8% vs. 84.2%), White (6.5% vs. 23%) and to speak English (33.3% vs. 80.6%) (all p < 0.001). Mean MPR was lower for post-SNAPS (0.68, SD = 0.33) compared to pre-SNAPS (0.89, SD = 0.22) (p = 0.001). Among post-SNAPS patients, cisgender men and MSM were more likely to be retained in PrEP care compared to cisgender women (p < 0.05). Although SNAPS linked diverse patients to PrEP-care, mean MPR was lower post-SNAPS compared to the pre-SNAPS. Continued investments to strengthen later stages of the PrEP cascade model for all populations vulnerable to HIV are needed.
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http://dx.doi.org/10.1007/s10461-025-04868-8 | DOI Listing |
AIDS Behav
September 2025
New York University School of Global Public Health, New York, NY, USA.
We developed and implemented a PrEP navigation program ("SNAPS") in a NYC safety-net hospital with the objectives to co-locate navigation, clinical PrEP services, and payment assistance. Adherence and retention to PrEP-related care were assessed by mean medication possession ratios (MPRs) and number of appointments over 12 months. Compared to the pre-SNAPS cohort, the post-SNAPS cohort was less likely to be cisgender male (64.
View Article and Find Full Text PDFJ Formos Med Assoc
September 2025
Department of Internal Medicine, National Taiwan University College of Medicine and National Taiwan University Hospital, Taipei, Taiwan; Department of Tropical Medicine and Parasitology, National Taiwan University College of Medicine, Taipei, Taiwan; Department of Internal Medicine, National Taiwan
Since 2010, high-risk sexual contact has become a major route of hepatitis C virus (HCV) transmission in Taiwan, particularly among men who have sex with men (MSM). With the rollout of direct-acting antivirals (DAAs) and the implementation of national strategies such as mass screening and reflex viral load testing to improve detection of HCV viremia, Taiwan has made substantial progress toward HCV elimination. Among MSM living with HIV, the prevalence, incidence, and reinfection rates of HCV have significantly declined following the implementation of the HCV elimination program.
View Article and Find Full Text PDFJMIR Public Health Surveill
August 2025
School of Medicine, University of North Carolina at Chapel Hill, 130 Mason Farm Rd, Chapel Hill, NC, 27599-6134, United States, 1 9199662536.
Background: In the United States, persisting new HIV diagnoses among gay, bisexual, and other cisgender men who have sex with men (GBMSM) and transgender women make it unlikely that the United States will meet the Ending the HIV Epidemic's (EHE) goal to reduce new HIV diagnoses by 90% by 2030. Innovative strategies are needed to address this challenge, particularly in the US South, where Black and Latinx GBMSM and transgender women are disproportionately impacted by HIV. Social network approaches have led to increased HIV testing uptake.
View Article and Find Full Text PDFJ Acquir Immune Defic Syndr
August 2025
Department of Work and Social Psychology, Maastricht University, Maastricht, the Netherlands.
Background: Long-acting injectable pre-exposure-prophylaxis (LAI-PrEP) offers potentials for expanding PrEP coverage and improving public health outcomes. This study synthesises evidence on the prevalence and determinants of interest in and preference for LAI-PrEP among men-who-have-sex-with-men (MSM), trans* individuals, and heterosexual women.
Methods: We conducted this systematic review and meta-analysis building on quantitative studies from a previous review and new studies published in PubMed, Web of Science, and Embase up to December 31, 2023.
BMC Health Serv Res
August 2025
Project-Malawi, University of North Carolina, Chapel Hill, Malawi.
Background: Elimination of vertical transmission of HIV remains a major global public health priority. In Malawi, more than one-third of pediatric HIV acquisitions are attributed to perinatal HIV acquisition during breastfeeding. HIV pre-exposure prophylaxis (PrEP) is a crucial biomedical tool to keep women free of HIV and eliminate vertical transmission, but effectiveness has been hampered by poor uptake and premature discontinuation.
View Article and Find Full Text PDF