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Article Abstract
The Nautilus intrasaccular system (EndoStream Medical, Israel) is a spiral-shaped neck-bridging endovascular device designed to support coiling of intracranial aneurysms [1-3]. It is deployed into the aneurysm sac through a 0.0165" or 0.017" microcatheter. Coils are delivered via a second microcatheter passed through the struts of the device. The system is available in 4-7-mm sizes and is entirely radio-opaque. It is mechanically detached and fully resheathable. Constructed from a nitinol wire with a platinum-based coil sleeve, it lacks a proximal marker. It has the lowest profile of current intrasaccular devices but a limited size range. Antiplatelet therapy is not mandatory. Limited published series and post-market data suggest high occlusion rates with low complication rates. The device may be particularly suitable for ruptured wide-necked aneurysms. This technical video discusses the device with the aid of two illustrative cases.
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How to use the nautilus intrasaccular system.
Interv Neuroradiol
September 2025
Department of Neuroradiology, Queen's Hospital, Greater London, UK.
The Nautilus intrasaccular system (EndoStream Medical, Israel) is a spiral-shaped neck-bridging endovascular device designed to support coiling of intracranial aneurysms [1-3]. It is deployed into the aneurysm sac through a 0.0165" or 0.
View Article and Find Full Text PDFIntrasaccular therapy in wide-neck intracranial aneurysms: a narrative review.
Front Neurol
July 2025
Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China.
The treatment of wide-neck intracranial aneurysms (WNIAs) is a challenge in interventional therapy. Intrasaccular therapy, including intrasaccular flow disruption or formation of a neck bridge within the saccular, has been extensively used recently. The Medina® Embolisation Device, Luna™ Aneurysm Embolisation System, Artisse™ Aneurysm Embolisation System, Contour Neurovascular System™, Neqstent™ Coil Assisted Flow Diverter, Woven EndoBridge (WEB) device, Nautilus™ Intrasaccular System, and Trenza Embolization Device™ have obtained Conformité Européene Mark certification.
View Article and Find Full Text PDFEndovascular treatment of wide-necked intracranial aneurysms using the Nautilus Intrasaccular System: initial case series of 41 patients at a single center.
J Neurointerv Surg
October 2023
Radiology Department, University Hospital St Ivan Rilski, Sofia, Bulgaria
Background: Endovascular treatment of intracranial wide-necked and bifurcation aneurysms (WNBA) is technically challenging. The Nautilus Intrasaccular System is designed to provide a mechanical barrier at the aneurysm neck to support coil embolization. We report the results of a single-center series of patients treated for intracranial aneurysms with the Nautilus.
View Article and Find Full Text PDFIntrasaccular neck-bridging: A technical note on Nautilus-assisted coiling of wide-necked cerebral aneurysms. Feasibility study, immediate and early angiographic results.
Interv Neuroradiol
December 2022
Interventional Radiology Department, UH St Ivan Rilski, Sofia, Bulgaria.
Purpose: Various adjunctive devices have been reported to be helpful during the endovascular coiling of complex, wide-necked cerebral aneurysms. This study aimed to describe the utilization of a recently introduced intrasaccular neck-bridging implant specifically designed to facilitate coil embolization.
Methods: We retrospectively reviewed eight consecutive patients who underwent treatment for intracranial aneurysms with the Nautilus intrasaccular bridging system between February 2022 to May 2022.
Nautilus-assisted coil embolization for a complex AcomA wide-necked aneurysm in the setting of acute subarachnoid hemorrhage.
J Neurointerv Surg
March 2022
Radiology Department, University Hospital St Ivan Rilski, Sofia, Sofiâ, Bulgaria
Numerous devices and sophisticated strategies have been developed to further increase the number of aneurysms amenable to endovascular treatment.1-4 Despite the superfluity of available neurovascular armamentarium, wide-necked bifurcation aneurysms can still pose a significant technical challenge to the treating clinician.5-7 Neck bridging is a conceptually new approach, which provides increased occlusion rates with lower recurrence and complications rates.
View Article and Find Full Text PDF