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http://dx.doi.org/10.5334/gh.1465 | DOI Listing |
Pain Rep
October 2025
Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Introduction: Moderate-to-severe acute postsurgical pain (APSP) is experienced by approximately 30% of surgical patients.
Objectives: To improve early APSP management, we developed 2 pragmatic and generalizable point-of-care risk tools to preoperatively predict moderate-to-severe and severe APSP in the postanaesthesia care unit (PACU).
Methods: This was a multicenter prospective cohort study of adult patients undergoing elective surgical procedures between May 2021 and May 2023.
Glob Heart
September 2025
Cardio-Oncology Clinic, Baghdad Medical City, Baghdad, Iraq.
Neurol Clin Pract
October 2025
Department of Neurology, Division of Neurocritical Care and Emergency Neurology, Program in Trauma, University of Maryland, Baltimore, MD.
Background And Objectives: Guidelines for super-refractory status epilepticus (SRSE) evaluation, management, and prognostication are lacking. Characterization of practice patterns could identify trends and potential areas for future inquiry. We surveyed clinicians who manage SRSE to better understand practice approaches to SRSE evaluation, management, and prognostication.
View Article and Find Full Text PDFLancet Rheumatol
September 2025
Academic Rheumatology, University of Nottingham, Nottingham, UK.
Background: Allopurinol, the most prescribed urate-lowering drug, is a known cause of severe cutaneous adverse reactions. We aimed to develop and validate a model to assess the risk of allopurinol-induced severe cutaneous adverse reactions in adults newly prescribed allopurinol.
Methods: In this retrospective new-user cohort study, we developed and validated a prognostic model using primary care, hospitalisation, and mortality data extracted from the UK Clinical Practice Research Datalink (CPRD) primary care database, for the period Jan 1, 2001, to March 29, 2021.