Pragmatic, Patient-centered Decision Making Paired With Tailored Risk Mitigation Strategies.

Int J Radiat Oncol Biol Phys

Department of Nuclear Medicine, University Hospital Zurich, Zurich, Switzerland.

Published: October 2025


Category Ranking

98%

Total Visits

921

Avg Visit Duration

2 minutes

Citations

20

Article Abstract

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2025.03.084DOI Listing

Publication Analysis

Top Keywords

pragmatic patient-centered
4
patient-centered decision
4
decision making
4
making paired
4
paired tailored
4
tailored risk
4
risk mitigation
4
mitigation strategies
4
pragmatic
1
decision
1

Similar Publications

Background: Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) portends a devastating prognosis for patients, with survival typically being < 5 to 8 years after diagnosis. Limited clinical trial data exist to guide treatment strategies, and the efficacy of current strategies-immunomodulation and antifibrotics-remains uncertain. Large randomized controlled trials are costly, but pragmatic trial designs could reduce expenses.

View Article and Find Full Text PDF

Bronchiectasis is a heterogeneous lung disease. There is an increasing focus on personalised medicine in bronchiectasis, with targeted pharmacological interventions for inflammation, immunology and infection. Airway clearance techniques (ACTs) are non-pharmacological treatments used to manage bronchiectasis.

View Article and Find Full Text PDF

Importance: When randomized trials are unavailable or not feasible, observational studies can be used to answer causal questions about the comparative effects of interventions by attempting to emulate a hypothetical pragmatic randomized trial (target trial). Published guidance to aid reporting of these studies is not available.

Objective: To develop consensus based guidance for reporting observational studies performed to estimate causal effects by explicitly emulating a target trial.

View Article and Find Full Text PDF

Reimagining enhanced recovery after surgery (ERAS) - Towards innovative trial design and patient-centered outcomes.

Gynecol Oncol

September 2025

Division of Gynecologic Oncology, Mayo Clinic College of Medicine, Rochester, MN, USA; Robert D. and Patricia E. Kern Center for the Science of Healthcare Delivery, Mayo Clinic, Rochester, MN, USA. Electronic address:

View Article and Find Full Text PDF