Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Background: The ideal harvesting techniques of the left internal mammary artery (LIMA) for coronary artery bypass graft (CABG) are elusive. We assessed the safety and resource utilisation efficiency of semi-skeletonised LIMA harvesting techniques, focusing on length, harvesting time, and the number of Ligaclips used compared to skeletonised techniques within a single surgeon's practice.
Methods: The BANGABANDHU (Bangladeshi Atherosclerosis Biobank AND Hub) study was an ambispective observational cohort that evaluated age- and sex-matched 2209 adult Bangladeshi isolated CABG population from 1st January 2015 to 31 January 2025. Univariate analysis observed the difference pattern in the dataset, while multivariate logistic regression (LR) analysis identified the independent variables associated with the advantage of semi-skelitonised LIMA. The area under the receiver operating characteristic (AUROC) curve demonstrated the goodness-of-fit of the prediction model.
Results: We evaluated 2209 age- and sex-matched adult isolated CABG patients (skeletonised LIMA; n = 1050 and semi-skeletonised LIMA; n = 1159) with identical comorbidities (EuroSCORE II, hypertension, diabetes, renal impairment, COPD, left main and multivessel coronary artery disease) between study groups (p > 0.05). LIMA harvest time (35.9 ± 5.5 vs 16.6 ± 3.9; p < 0.001) and number of used Ligaclip (23.6 ± 4.8 vs 11.7 ± 3.6; p < 0.001) were significantly higher in the skeletonised compared to the semi-skeletonised LIMA sample. Furthermore, an age and sex-adjusted multivariate logistic regression model found LIMA harvest time (odds ratio [OR] 0.067, 95% CI 0.01-0.39; p = 0.003) and number of used Ligaclip (OR 0.561, 95% CI 0.41-0.76; p < 0.001) significantly lower among semi-skeletonised LIMA techniques.
Conclusion: The semi-skeletonised LIMA technique is advantageous as it significantly reduces harvesting time and requires fewer Ligaclips compared to the skeletonised technique.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12412939 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0331285 | PLOS |
Publication Analysis
Top Keywords
Similar Publications
A neural circuit from hypothalamic paraventricular oxytocin neurons to trigeminal nucleus caudalis GABAergic neurons modulates pain sensitization in a mouse model of chronic migraine.
Zhejiang Da Xue Xue Bao Yi Xue Ban
September 2025
Institute of Brain Science and Disease Research Institute, Qingdao University, Qingdao 266075, Shandong Province, China.
Objectives: To investigate the role of a neural pathway from oxytocin (OXT) neurons in the hypothalamic paraventricular nucleus (PVN) to γ-aminobutyric acid (GABA) neurons in the trigeminal nucleus caudalis (TNC) in regulating pain sensitization in a mouse model of chronic migraine and to explore the underlying mechanisms.
Methods: A chronic migraine model was established by intraperitoneal injection of nitroglycerin (NTG, 10 mg/kg) on days 1, 3, 5, 7, and 9. The study consisted of four parts: PartⅠ: Wild-type C57BL/6J mice were divided into 4 groups (=6 in each), receiving single or repeated injection of NTG or saline, respectively.
Impact of Serum/Xeno-Free Medium and Cytokine Supplementation on CAR-T Cell Therapy Manufacturing in Stirred Tank Bioreactors.
Biotechnol J
September 2025
Department of Biochemical Engineering, University College London, London, UK.
Chimeric antigen receptor T-cell (CAR-T) therapies have demonstrated clinical efficacy in treating haematological malignancies, resulting in multiple regulatory approvals. However, there is a need for robust manufacturing platforms and the use of GMP-aligned reagents to meet the clinical and commercial demands. This study investigates the impact of serum/xeno-free medium (SXFM) and cytokine supplementation on CAR-T cell production in static and agitated culture systems, using 24-well plate G-Rex vessels and 500 mL stirred tank bioreactors (STRs), respectively.
View Article and Find Full Text PDFAssessing environmental and management factors that drive soybean yield gaps in Brazil.
J Environ Qual
September 2025
Department of Crop Science, Federal University of Santa Maria, Santa Maria, Brazil.
Brazil is the world's largest producer and exporter of soybeans (Glycine max L. Merr.).
View Article and Find Full Text PDFRecent Developments Towards Sustainable Solutions in Electrospun Active Packaging Systems for Various Foods.
Compr Rev Food Sci Food Saf
September 2025
Department of Seafood Processing Technology, Faculty of Fisheries, Cukurova University, Adana, Turkey.
Microbial spoilage and oxidation are significant causes of food deterioration, contributing to food waste of up to 30%. To mitigate these losses, active food packaging is an effective solution. Considering the excellent properties of nanofibers produced by electrospinning, integrating active food packaging functionality with nanofiber technology offers an ideal approach enhancing preservation.
View Article and Find Full Text PDFCherry-Net: real-time segmentation algorithm of cherry maturity based on improved PIDNet.
Front Plant Sci
September 2025
College of Big Data, Yunnan Agricultural University, Kunming, China.
Introduction: Accurate identification of cherry maturity and precise detection of harvestable cherry contours are essential for the development of cherry-picking robots. However, occlusion, lighting variation, and blurriness in natural orchard environments present significant challenges for real-time semantic segmentation.
Methods: To address these issues, we propose a machine vision approach based on the PIDNet real-time semantic segmentation framework.