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The brain-computer interface (BCI) system facilitates efficient communication and control, with Electroencephalography (EEG) signals as a vital component. Traditional EEG signal classification, based on static deeplearning models, presents a challenge when new classes of the subject's brain activity emerge. The goal is to develop a model that can recognize new few-shot classes while preserving its ability to discriminate between existing ones. This scenario is referred to as Few-Shot Class-Incremental Learning (FSCIL). This work introduces IncrementEEG, a novel framework meticulously designed to tackle the distinct challenges of FSCIL in EEG-based brain activity classification, focusing specifically on emotion recognition and steady-state visual evoked potential (SSVEP). Our work analyzes the role of additive angular margin loss in improving the model's discrimination capabilities. The proposed method is designed to demonstrate robustness in open-world conditions and adaptability to new tasks. Furthermore, we introduce a prototype refinement module comprising a prototype augmentation block and an update block. The prototype augmentation block in the deep feature space preserves the decision boundary for prior tasks, and the prototype update block utilizes a shared embedding space to compute the relation matrix for bootstrapping prototype updates. Extensive experiments conducted across multiple datasets show the superior performance of the IncrementEEG framework compared to state-of-the-art methods. The proposed method advances FSCIL brain activity classification, offering promising potential for applications in Brain-Computer Interface systems.
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http://dx.doi.org/10.1109/JBHI.2025.3605108 | DOI Listing |
Arch Pharm Res
September 2025
College of Pharmacy, Hanyang University, Ansan, 15588, Republic of Korea.
c-Jun N-terminal kinases (JNKs), a subfamily of mitogen-activated protein kinases (MAPKs), are key mediators of cellular responses to environmental stress, inflammation, and apoptotic signals. The three isoforms-JNK1, JNK2, and JNK3 exhibit both overlapping and isoform-specific functions. While JNK1 and JNK2 are broadly expressed across tissues and regulate immune signaling, cell proliferation, and apoptosis, JNK3 expression is largely restricted to the brain, heart, and testis, where it plays a crucial role in neuronal function and survival.
View Article and Find Full Text PDFMetab Brain Dis
September 2025
Department of Pharmacology and Toxicology, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Acute or chronic liver damage can result in Hepatic Encephalopathy (HE), a potentially fatal neuropsychiatric condition that leads to cerebral and neurological alterations. Dapagliflozin (DAPA), an orally active Sodium/Glucose cotransporter 2 inhibitor with long duration of action. The study aim was to evaluate the potential protective impact of DAPA against HE caused by Thioacetamide (TAA) in rats.
View Article and Find Full Text PDFNeurochem Res
September 2025
International Translational Neuroscience Research Institute, Zhejiang Chinese Medical University, Hangzhou, 310053, Zhejiang, China.
The concept of the central nervous system (CNS) reserve emerged from the mismatch often observed between the extent of brain pathology and its clinical manifestations. The cognitive reserve reflects an "active" capacity, driven by the plasticity of CNS cellular components and shaped by experience, learning, and memory processes that increase resilience. We propose that neuroglial cells are central to defining this resilience and cognitive reserve.
View Article and Find Full Text PDFJ Neurol
September 2025
Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background: The "Systematic Screening of Handwriting Difficulties in Parkinson's Disease" (SOS) test is the only tool specifically designed to evaluate handwriting in people with Parkinson's Disease (pwPD). It is language specific.
Objective: To assess the construct validity, intrarater and interrater reliability of the Italian version of the SOS test.
Elife
September 2025
Center for Mind and Brain, University of California, Davis, Davis, United States.
Visual search relies on the ability to use information about the target in working memory to guide attention and make target-match decisions. The 'attentional' or 'target' template is thought to be encoded within an inferior frontal junction (IFJ)-visual attentional network. While this template typically contains veridical target features, behavioral studies have shown that target-associated information, such as statistically co-occurring object pairs, can also guide attention.
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