Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The primary goal of breast conservation surgery (BCS) is to achieve tumour-free margins. However, it is known that in 20% patients, a tumour-free margin may not be obtained. Positive margins frequently lead to re-operation and are the strongest predictors of local recurrence. We therefore evaluated the performance of ultrasound (US) and frozen section (FS) in predicting the margin status of lumpectomy specimens of ultrasound-detectable breast carcinoma patients undergoing BCS. In our prospective study on 54 patients who underwent lumpectomy, the margins were analyzed by ultrasound and frozen section. Patient-wise and margin-wise diagnostic parameters were calculated for both modalities.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/00494755251374479 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Three-dimensional histological electrophoresis with fluorescence labeling for detection of malignant tissue contours in precise conserving surgery.
Anal Chim Acta
November 2025
Department of Breast Surgery, General Surgery Center, First Hospital of Jilin University, Changchun, PR China. Electronic address:
Background: Breast-conserving surgery (BCS) is the primary surgical approach for patients with breast cancer. The accurate determination of surgical margins during BCS is critical for patient prognosis; however, time constraints and limitations in current pathological techniques often prevent pathologists from performing this assessment intraoperatively. The inability to reliably assess margins during surgery can lead to incomplete tumor removal and the need for additional surgeries.
View Article and Find Full Text PDFA comparative evaluation of ultrasound and frozen section analysis in predicting margin status after breast conservation surgery in patients with ultrasound-detectable breast cancer.
Trop Doct
September 2025
Professor, Department of Pathology, All India Institute of Medical Sciences, Patna, India.
The primary goal of breast conservation surgery (BCS) is to achieve tumour-free margins. However, it is known that in 20% patients, a tumour-free margin may not be obtained. Positive margins frequently lead to re-operation and are the strongest predictors of local recurrence.
View Article and Find Full Text PDFEctopic adrenal gland in the liver leading to a misdiagnosis of hepatocellular carcinoma: A case report.
World J Hepatol
August 2025
Department of General Surgery, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, Guangdong Province, China.
Background: Adrenal ectopia is a rare condition in which adrenal tissue is found in an abnormal location, often posing diagnostic challenges. Although generally considered benign, it can present as hepatic or other organ lesions, mimicking malignant tumors. In the liver, ectopic adrenal tissue can closely resemble hepatocellular carcinoma or metastatic disease, potentially leading to unnecessary aggressive treatments such as surgery or chemotherapy.
View Article and Find Full Text PDFMalignant transformation of struma ovarii into follicular thyroid carcinoma: A case report.
Medicine (Baltimore)
August 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, Saga University, Saga, Japan.
Rationale: Struma ovarii is a rare form of mature cystic teratoma, with malignant transformation reported in approximately 5% to 10% of cases. Transformation into follicular thyroid carcinoma (FTC) is extremely uncommon; as a result, no standardized guidelines exist for treatment or prognosis for such cases.
Patient Concerns: A 54-year-old woman with cholelithiasis presented with upper abdominal discomfort.
Fibula single-tunnel versus fibula double-tunnel for both anterior talofibular ligament and calcaneofibular ligament reconstruction: a biomechanical comparison.
BMC Musculoskelet Disord
September 2025
Orthopedic and Traumatology Department, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Background: Anatomic ligament repair surgery, despite being a tremendous technical challenge in treating chronic lateral ankle instability patients, remains the gold standard for this condition. The fibula single-tunnel and double-tunnel techniques are effective for intraoperative reconstruction of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL). However, which approach is more appropriate is a subject of debate.
View Article and Find Full Text PDF