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Research indicates that psychotic-like experiences (PLEs) are associated with sleep problems, which in turn may contribute to negative outcomes in individuals with PLEs. This study examined the association between sleep problems and PLEs in the Japanese general population, and whether sleep problems are linked to loneliness among individuals with PLEs. Data were analyzed from 3717 adults aged 18 and above who participated in an online survey in 2023. PLEs were assessed with the PRIME Screen-Revised (PS-R), while a single-item self-report measure was used to assess the intensity of sleep problems. Logistic regression analyses were conducted to examine the associations. In an analysis that was adjusted for sociodemographic, physical, and mental health variables, compared to those with no sleep problems, only individuals who reported extreme sleep problems had significantly higher odds of PLEs (OR: 2.93, 95 %CI: 1.38-6.23). An analysis examining the role of sleep problems in the association between PLEs and loneliness showed that PLEs were significantly associated with loneliness only when accompanied by extreme sleep problems (OR: 4.45, 95 % CI: 1.12-17.70), with no significant association observed in their absence (OR: 1.12, 95 % CI: 0.74-1.69). Extreme sleep problems are associated with PLEs in Japanese adults. Furthermore, among adults with PLEs, extreme sleep problems may contribute to loneliness. These findings suggest that identifying and treating sleep difficulties in Japanese adults with PLEs may yield benefits that extend beyond sleep outcomes alone.
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http://dx.doi.org/10.1016/j.psychres.2025.116705 | DOI Listing |
J Integr Neurosci
August 2025
Neurological Institute of Jiangxi Province and Department of Neurology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, and Xiangya Hospital of Central South University at Jiangxi, 330038 Nanchang, Jiangxi, China.
Sleep paralysis, colloquially known as "ghost pressing" is a state of momentary bodily immobilization occurring either at the onset of sleep or upon awakening. It is characterized by atonia during rapid eye movement (REM) sleep that continues into wakefulness, causing patients to become temporarily unable to talk or move but possessing full consciousness and awareness of their surroundings. Sleep paralysis is listed in the International Classification of Sleep Disorders, 3rd Edition (ICSD-3) as a parasomnia occurring during REM sleep that be classified as either isolated or narcolepsy-associated.
View Article and Find Full Text PDFSleep Adv
June 2025
Academic Rheumatology, Injury Recovery and Inflammation Sciences, School of Medicine, University of Nottingham, Nottingham, UK.
Study Objectives: To examine whether there is a temporal association between sleep disturbance and multimorbidity.
Methods: We performed a cross-sectional and longitudinal observational analysis in people aged 40 years or more, recruited from the knee pain and related health in the community cohort study. The primary exposure was the Sleep Problems Index II score in tertiles measured at baseline.
Cancer Rep (Hoboken)
September 2025
Department of Respiratory and Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou Dushu Lake Hospital, Medical Centre of Soochow University, Suzhou, Jiangsu, China.
Background: Epigenetic regulation significantly affects immune responses in lung adenocarcinoma (LUAD). However, the role of RNA N6-methyladenosine (m6A) modification, especially in obstructive sleep apnea-hypopnea syndrome (OSAHS) within LUAD, is not well understood.
Methods: This study examined m6A modification patterns in 973 LUAD patients using 23 regulatory genes.
Nan Fang Yi Ke Da Xue Xue Bao
August 2025
Department of Nursing, Shenzhen Hospital, Southern Medical University, Shenzhen 518101, China.
Objectives: To investigate the therapeutic effect of acupuncture in a rat model of insomnia and its regulatory effect on the glutamic acid (Glu)/γ-aminobutyric acid (GABA)-glutamine (Gln) metabolic loop.
Methods: Forty male SD rats were randomly assigned to control group, model group, group and group (=10). In the latter 3 groups, rat models of insomnia were established by intraperitoneal injections of p-chlorophenylalanine and verified using a sodium pentobarbital-induced sleep test.
Nihon Eiseigaku Zasshi
September 2025
Department of Hygiene, Public Health and Preventive Medicine, Showa Medical University School of Medicine, Tokyo, Japan.
Objective: In this study, we aimed to examine the relationship between the Eating Assessment Tool-10 (EAT10) score, a screening index for dysphagia, and the Epworth Sleepiness Scale (ESS) score, which evaluates daytime sleepiness in Japanese workers.
Method: A cross-sectional study of 496 workers (454 men and 42 women) at two business locations in Japan was conducted from November 2021 to June 2022. Dysphagia was assessed using the score of EAT10, a self-administered questionnaire.