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Purpose: The aim of this study was to investigate the effects of 3 months of seated Tai Chi (TC) practice on the eye-hand coordination and sitting balance control of subjects with Parkinson's disease.
Method: A prospective non-randomized study was conducted with 29 subjects practicing TC and 27 subjects as controls according to their preference. The seated TC group underwent 3 months of training with a total of 24 sessions (1hour/session, 2 sessions/week). The outcome measures included a dynamic finger pointing task (reaction time, movement time, and accuracy), and a sequential weight shifting balance control test (completion time) while seated.
Results: The TC group showed faster movement time in the dynamic finger pointing task (p = 0.003). They also achieved a faster completion time of the sequential weight shifting balance test (p = 0.021). No significant difference was observed in the control group.
Conclusions: The results demonstrate that 3 months of seated TC training could improve movement time in the finger pointing task and sitting balance control in subjects with Parkinson's disease. A future randomized controlled trial is warranted.
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http://dx.doi.org/10.1159/000547567 | DOI Listing |
Arch Phys Med Rehabil
September 2025
Department of Rehabilitation Medicine, Wuxi Central Rehabilitation Hospital, The Affiliated Mental Health Center of Jiangnan University, Wuxi, Jiangsu, China. Electronic address:
Objective: To identify baseline factors linked to a positive response to intermittent theta-burst stimulation (iTBS) in individuals with stroke.
Design: Secondary analysis of a randomized controlled trial.
Setting: A single rehabilitation hospital.
An Pediatr (Engl Ed)
September 2025
Sección de Urgencias de Pediatría, Hospital Universitario Basurto, Bilbao, Vizcaya, Spain. Electronic address:
J Affect Disord
September 2025
Department of Neuroscience and Anatomy, Virginia Commonwealth University School of Medicine, Richmond, VA, USA. Electronic address:
Transposable elements (TEs) are repetitive DNA sequences capable of being transcribed and re-integrated, or transposed, into distinct loci throughout the genome. While thought to be largely transcriptionally silenced in brain, TE transcription is increasingly recognized as dynamic and involved in human health and disease states, including in disorders of the brain. In this study, we annotated TE transcripts in publicly available RNA sequencing (RNAseq) of postmortem human brain tissue to investigate the expression profile of TE transcripts in individuals with major depressive disorder (MDD) compared to healthy controls.
View Article and Find Full Text PDFCureus
August 2025
Medicine, Donesk National Medical University, Donesk, UKR.
Autoimmune diseases (AIDs) are multifaceted, chronic illnesses characterized by immune dysregulation and systemic inflammation. Newer evidence has pointed a finger at the human gut microbiota, a trillion-fold population of microorganisms that inhabits the human GI tract, as a major influential modulator of immune reactivity and a significant contributor to autoimmune pathogenesis. This systematic review will seek to address how the literature correlates with systematic changes in the gut microbiota in AIDs as well as explore mechanistic associations with biological processes like intestinal permeability and modulation of the immune system, coupled with determining the effectiveness of microbiota-directed interventions.
View Article and Find Full Text PDFPurpose: The aim of this study was to investigate the effects of 3 months of seated Tai Chi (TC) practice on the eye-hand coordination and sitting balance control of subjects with Parkinson's disease.
Method: A prospective non-randomized study was conducted with 29 subjects practicing TC and 27 subjects as controls according to their preference. The seated TC group underwent 3 months of training with a total of 24 sessions (1hour/session, 2 sessions/week).