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Article Abstract
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12383868 | PMC |
| http://dx.doi.org/10.3390/biology14080991 | DOI Listing |
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Correction: Thu et al. Effect of Probiotics in Breast Cancer: A Systematic Review and Meta-Analysis. 2023, , 280.
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There was an error in the original publication [...
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The efficacy of biologics, such as peptide and protein drugs, is often limited by their short half-lives in vivo, necessitating repeated infusions to maintain therapeutic effects. Here, we demonstrate that long-lived CAR T cells can be leveraged as a versatile platform for long-term delivery of biologics. Our recent findings show that the depletion of BCOR and ZC3H12A induces GD2 CAR T cells into an immortal-like and functional state, which we have termed GD2T cells.
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