Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3165
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 597
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 511
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 317
Function: require_once
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Background: Fluid overload-a critical risk in pediatric/neonatal care-is often driven by excessive fluid during medication dilution, increasing complications like acute kidney injury(AKI), prolonged ventilation, and mortality.
Methods: A 2024 cross-sectional study across 14 pediatric units (PICUs, NICUs, surgical/general wards) evaluated fluid administration practices and nurses' knowledge. Observations included 150 patients and 200 nurses administering 8 medications. Data on fluid volumes, infusion durations, compatibility, and storage compliance were collected via checklist and questionnaires.
Results: Nurses demonstrated moderate overall knowledge (mean score: 68.3 ± 10.4), with unit-level variability. Performance scores were highest in PICUs (76.0 ± 9.7) and lowest in surgical wards (62.86 ± 12.7). Key issues included excessive dilution (vancomycin, ampicillin, ceftriaxone) and storage noncompliance (eg, 40% in cardiac NICUs), posing risks to vulnerable patients.
Conclusion: Standardized dilution guidelines, enhanced education on drug compatibility/storage, and real-time monitoring tools are critical to mitigating fluid overload risks and improving pediatric outcomes.
Download full-text PDF |
Source |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12402650 | PMC |
http://dx.doi.org/10.1177/30502225251364933 | DOI Listing |