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The differential diagnosis of sinonasal lesions includes benign and malignant disease. Current radiologic diagnosis depends on the complementary roles of CT and MRI. PET/CT has been widely utilized for diagnosis and staging of various types of tumors as well as assessing treatment response. This article summarizes distinguishing radiologic characteristics of sinonasal disease, including lesions that are FDG avid (squamous cell carcinoma, lymphoma, inverted papilloma, rhabdomyosarcoma, osteosarcoma, and sinusitis), lesions that express somatostatin receptors (meningioma, esthesioneuroblastoma, and juvenile nasopharyngeal angiofibroma), and lesions that are not FDG avid (mucocele, mucus retention cyst, and sinus meningoencephalocele). Furthermore, PET/MRI may better facilitate the diagnosis of sinonasal disease.
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http://dx.doi.org/10.1097/RLU.0000000000006101 | DOI Listing |
Clin Nucl Med
September 2025
Department of Radiology, Division of Neuroradiology, University of Miami Miller School of Medicine, Jackson Memorial Hospital, Miami, FL.
The differential diagnosis of sinonasal lesions includes benign and malignant disease. Current radiologic diagnosis depends on the complementary roles of CT and MRI. PET/CT has been widely utilized for diagnosis and staging of various types of tumors as well as assessing treatment response.
View Article and Find Full Text PDFLaryngoscope
September 2025
Department of Otolaryngology-Head and Neck Surgery, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, New York, USA.
Objectives: Inverted papilloma (IP) is typically a benign sinonasal tumor with a propensity to recur. The surgical treatment of IP arising from the frontal sinus is complicated by proximity to the orbit and skull base. The objective of this study is to describe the surgical challenges when managing this disease and report treatment outcomes in a multicenter cohort.
View Article and Find Full Text PDFLaryngoscope
September 2025
Department of Otolaryngology - Head and Neck Surgery, School of Medicine, Showa Medical University, Tokyo, Japan.
We report a rare case of a sterile nasal septal abscess (NSA) occurring as an extraintestinal manifestation of ulcerative colitis (UC), accompanied by a novel histopathologic finding. A 40-year-old woman with relapsed UC presented with nasal swelling, purulent discharge, hematochezia, and skin lesions. Computed tomography revealed an anterior NSA, and emergent endoscopic drainage was performed.
View Article and Find Full Text PDFZhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
August 2025
Department of Otolaryngology Head and Neck Surgery, Hunan Province Key Laboratory of Otolaryngology Critical Diseases, National Clinical Research Center for Geriatric Disorders, Xiangya Hospital of Central South University, Changsha 410008, China.
To retrospectively analyze the cases of inflammatory myofibroblastic tumor (IMT) involving the sinonasal skull base, and to investigate their clinical characteristics, diagnostic approaches, and treatment outcomes, in order to improve understanding of this rare entity. Clinical data from five patients with pathologically confirmed sinonasal skull base IMT who underwent surgical treatment at Xiangya Hospital of Central South University between April 2010 and June 2023 were reviewed. Information on clinical presentation, laboratory findings, imaging features, histopathological and immunohistochemical results, treatment strategies, and follow-up outcomes was collected.
View Article and Find Full Text PDFHNO
September 2025
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital and University of Zurich, Zurich, Switzerland.
Eosinophilic granulomatosis with polyangiitis (EGPA, previously known as Churg-Strauss syndrome) is an antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) often presenting with chronic rhinosinusitis, pulmonary infiltrates, gastrointestinal and cardiac disorders, or renal lesions. Sinonasal and inner ear manifestations are common, but other affections of the head and neck area are rarely reported. Here we report a case of a young woman with a histopathological diagnosis of eosinophil-rich granulomatous inflammation affecting solely the tongue without other local or systemic lesions.
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