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Introduction: Mentorship is increasingly recognized as a foundational stone within Graduate Medical Education (GME), contributing to clinical competency, scholarly engagement, professional identity formation, and psychological well-being. Despite its growing recognition, mentorship in GME remains inconsistently structured, under-theorized, and variably evaluated. This conceptual and structural ambiguity hampers the ability to design, compare, and scale mentorship efforts meaningfully across settings. This scoping review aimed to systematically explore the structure, theoretical foundations, evaluation approaches, and reported outcomes of mentorship programs in GME, and to develop a conceptual framework to guide the design of context-sensitive, outcome-aligned mentorship interventions.
Methods: The scoping review followed Arksey and O'Malley's five-stage methodology and the findings were reported according to PRISMA-ScR guidelines. A comprehensive search of PubMed, Scopus, CINAHL, and Embase was conducted in January 2025, covering studies published between 2015 and 2025. Eligibility was defined using the Population-Concept-Context framework. Data were extracted using a structured template and synthesized thematically.
Results: A total of 94 studies were included. Mentorship programs varied widely in structure, with formal, informal, peer, and near-peer models observed. Only 27 studies reported use of theoretical frameworks, and evaluation approaches were often limited to non-validated tools and descriptive outcomes. Four main analytical clusters emerged: program structure, theoretical/conceptual frameworks, evaluation approaches, and reported outcomes. Outcomes commonly reported included career development, academic productivity, clinical competency, leadership, well-being, and professional growth. However, the main highlight was a lack of theoretical underpinnings, standardized outcome measurement and mentor training. Cultural responsiveness and equity were rarely considered in mentorship programs.
Conclusion: This scoping review highlights the need for mentorship programs in GME to be more systematically designed, theory-informed, and rigorously evaluated. Key gaps include the underutilization of conceptual models, the lack of validated evaluation tools, and insufficient attention to mentor training and equity considerations. Building on the findings of this scoping review, we propose a conceptual framework that aligns mentorship models with learner level, skill focus, and mentoring format across psychological and sociological domains. This framework is intended to guide the development of robust, context-sensitive, and theory-informed mentorship programs with measurable outcomes, ultimately fostering sustainable mentorship cultures that enhance learner development and improve healthcare practice in Graduate Medical Education (GME).
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http://dx.doi.org/10.3389/fmed.2025.1616148 | DOI Listing |
Top Curr Chem (Cham)
September 2025
Department of Organic Chemistry I, Faculty of Pharmacy and Lascaray Research Center, University of the Basque Country (UPV/EHU), Paseo de La Universidad 7, 01006, Vitoria-Gasteiz, Spain.
Aziridines, structurally related to epoxides, are among the most challenging and fascinating heterocycles in organic chemistry due to their increasing applications in asymmetric synthesis, medicinal chemistry, and materials science. These three-membered nitrogen-containing rings serve as key intermediates in the synthesis of chiral amines, complex molecules, and pharmaceutically relevant compounds. This review provides an overview of recent progress in catalytic asymmetric aziridination, focusing on novel methodologies, an analysis of the scope and limitations of each approach, and mechanistic insights.
View Article and Find Full Text PDFJ Nephrol
September 2025
Department of Cardiovascular Sciences, University of Leicester, John Walls' Renal Unit, University Hospitals of Leicester NHS Trust, Leicester, UK.
Background: Individuals with kidney failure experience elevated cardiovascular risk, potentially worsened by the presence of sleep disordered breathing. Despite this association, prevalence of sleep apnoea, and evidence for effective treatments are poorly understood in people with kidney failure. This review examines sleep apnoea prevalence, types of sleep apnoea, and treatment interventions in people with kidney failure receiving dialysis.
View Article and Find Full Text PDFEur J Appl Physiol
September 2025
Department of Occupational Health, Psychology, and Sports Sciences, University of Gavle, Gävle, Sweden.
Aim: To summarize the literature on quantitative measures of physical demands in eldercare, with attention to differences between temporary and permanent workers, and to identify gaps to guide future physiological research.
Methods: We searched Scopus, Web of Science, and PubMed for English and Swedish peer-reviewed studies on physical demands in eldercare. Risk of bias was assessed, and descriptive data extracted.
Nat Microbiol
September 2025
Joan and Sanford I. Weill Department of Medicine, Gastroenterology and Hepatology Division, Weill Cornell Medicine, New York, NY, USA.
Microbial influence on cancer development and therapeutic response is a growing area of cancer research. Although it is known that microorganisms can colonize certain tissues and contribute to tumour initiation, the use of deep sequencing technologies and computational pipelines has led to reports of multi-kingdom microbial communities in a growing list of cancer types. This has prompted discussions on the role and scope of microbial presence in cancer, while raising the possibility of microbiome-based diagnostic, prognostic and therapeutic tools.
View Article and Find Full Text PDFBDJ Open
September 2025
Operative Dentistry & Endodontics, Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan.
Background: Artificial Intelligence (AI) has become increasingly integrated into dental diagnostics, particularly for detecting carious lesions. While AI offers benefits such as improved accuracy and efficiency, its use raises important ethical concerns, including transparency, patient privacy, autonomy, diversity and accountability. This scoping review aims to identify these ethical concerns using a structured ethical framework.
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