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Purpose: To assess the value of routine annual imaging in identifying complications more than 5 years after radical cystectomy (RC) with ileal conduit.
Methods: We included patients with bladder cancer who underwent RC with ileal conduit between 2011 and 2018. Patients were excluded if they received no functional follow up after discontinuing oncological follow up, if there was oncological progression or if an uretero-enteric structure (UES) was diagnosed within 5 years after RC. Functional follow up consisted of annual imaging using either ultrasound or CT, along with laboratory tests. The primary outcomes were: (1) the incidence of new or progressive hydronephrosis, and (2) the incidence of imaging-diagnosed complications i.e. UES and urolithiasis.
Results: A total of eighty-two patients were included, with a mean follow up of 6.5 years after RC. In total, 202 ultrasounds and 71 CTs were performed. New or progressive hydronephrosis was observed in 6 imaging modalities (2.2%), in 6 different patients (7.3%). No UES cases were diagnosed following routine annual imaging. One patient was diagnosed with UES after diagnostic imaging was prompted by clinical symptoms.
Conclusion: In our cohort, routine annual imaging beyond five years after radical cystectomy (RC) with ileal conduit rarely revealed abnormalities and did not contribute to the diagnosis of UES nor urolithiasis. However, imaging should be performed when clinically indicated.
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http://dx.doi.org/10.1007/s00345-025-05903-y | DOI Listing |
JAMA
September 2025
Division of Surgery and Interventional Science, UCL, London, United Kingdom.
Importance: Multiparametric magnetic resonance imaging (MRI), with or without prostate biopsy, has become the standard of care for diagnosing clinically significant prostate cancer. Resource capacity limits widespread adoption. Biparametric MRI, which omits the gadolinium contrast sequence, is a shorter and cheaper alternative offering time-saving capacity gains for health systems globally.
View Article and Find Full Text PDFJB JS Open Access
September 2025
Department of Orthopaedic Surgery, St. Luke's University Health Network, Bethlehem, Pennsylvania.
Background: The use of artificial intelligence platforms by medical residents as an educational resource is increasing. Within orthopaedic surgery, older Chat Generative Pre-trained Transformer (ChatGPT) models performed worse than resident physicians on practice examinations and rarely answered questions with images correctly. The newer ChatGPT-4o was designed to improve these deficiencies but has not been evaluated.
View Article and Find Full Text PDFParkinsonism Relat Disord
September 2025
Clinical Neurosciences, University of Turku, Turku, Finland; Neurocenter, Turku University Hospital, Turku, Finland. Electronic address:
Introduction: Sarcopenia, the age-related loss of muscle mass and function, has been reported in Parkinson's disease (PD). While grip strength is a key marker of sarcopenia and has been linked to PD risk and progression, its relationship with underlying neurodegenerative processes remains unclear. This study examines whether grip strength is impaired in PD and reflects disease severity or dopaminergic function.
View Article and Find Full Text PDFAlcohol Clin Exp Res (Hoboken)
September 2025
Neurodevelopmental Laboratory on Addictions and Mental Health, McLean Hospital, Belmont, Massachusetts, USA.
Background: Examining youth before engagement in risky behaviors may help identify neurobiological signatures that prospectively predict susceptibility to initiating and escalating alcohol and other substance use. Given that frontal and medial temporal (e.g.
View Article and Find Full Text PDFPLoS One
September 2025
Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
Background: Stroke is a leading cause of death and disability globally, with frequent cognitive sequelae affecting up to 60% of stroke survivors. Despite the high prevalence of post-stroke cognitive impairment (PSCI), early detection remains underemphasized in clinical practice, with limited focus on broader neuropsychological and affective symptoms. Stroke elevates dementia risk and may act as a trigger for progressive neurodegenerative diseases.
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