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Introduction: The 2018 U.S. Farm Bill unintentionally resulted in the proliferation of derived intoxicating cannabis vape products (DICVPs), raising concerns about associated health risks. To inform prevention efforts, this study analyzed the product attributes and marketing features of DICVPs sold online, particularly features that could attract youth or lower risk perception.
Methods: In 2023, product attributes and descriptions of 490 flavored DICVPs were extracted from two online retail websites. In 2024, two trained coders thematically coded product descriptions for their product marketing features.
Results: Overall, 95 unique brands and 26 unique intoxicating cannabinoids were identified. The most frequent marketing features overall were vape product design and use (99.0%), including vaping satisfaction, discreetness, convenience, and use instructions. Regulation and compliance messages (91.6%) were also prevalent, including lab testing for additives and/or chemicals, health warnings, hemp-derived labels, references to the Farm Bill, and U.S. Food and Drug Administration approval statements. Other prominent themes included: flavor and sensation claims (79.6%, i.e., flavor variety, fruit flavors); psychoactive effect claims (43.3%, e.g., potency or expected user experience); product quality claims (38.4%, e.g., "quality," "natural," "purity"); and other positive effect claims (33.9%, e.g., mood enhancement, relaxation).
Discussion: The DICVP online marketplace is highly fragmented with a variety of brands and intoxicating compounds. Common marketing strategies promoting appealing flavors and positive vaping experiences may increase their appeal to young people. Features related to product legality and quality may reduce perceived risks and barriers to using products. Continuous monitoring of the DICVP marketplace is needed to inform policymaking.
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http://dx.doi.org/10.1080/10826084.2025.2555499 | DOI Listing |
Probiotics Antimicrob Proteins
September 2025
Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247 667, India.
Ethnic fermented foods represent a significant repository for discovering novel probiotic entities. These fermented foods, entrenched in indigenous practices, have conserved a distinct microbiota through generations. Exploration of these fermented foods could yield microbial consortia capable of transforming human health.
View Article and Find Full Text PDFApoptosis
September 2025
State Key Laboratory of Resource Insects, Medical Research Institute, Southwest University, Chongqing, 400715, China.
Colorectal cancer (CRC) is one of the most common and lethal malignancies worldwide, with treatment failure often attributed to chemoresistance and evasion of apoptosis. Cathayanon E (CE), a natural chalcone derivative isolated from Morus alba, has shown anticancer potential, but its role and mechanism in CRC remain largely unexplored. In this study, CE significantly inhibited CRC cell proliferation and induced apoptosis both in vitro and in vivo.
View Article and Find Full Text PDFJ Am Coll Radiol
August 2025
Vice-Chair for Clinical Research, John Westgate Hope Endowed Chair for Faculty Development, Department of Radiology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; Assistant Professor of Radiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsyl
Objective: To determine the number of pediatric radiologists in the United States using professional imaging claims of children between 2016 and 2023 in a private payor claims database.
Methods: From 2016 to 2023, using private payer claims data (Inovalon Insights, LLC), all claim lines for radiology professional services billed by radiologists were identified. Each claim was assigned a work relative value unit (wRVU) in accordance with the CMS valuation for the claim year.
Int J Phytoremediation
September 2025
Innovative Food Technologies Development Application and Research Center, Gölköy Campus Bolu, Bioenvironment and Green Synthesis Research Group, Bolu Abant İzzet Baysal University, Bolu, Türkiye.
This study presents an eco-friendly approach for the green synthesis of manganese oxide nanoparticles (MnONPs) using () (einkorn wheat) seed extract as a reducing and stabilizing agent. The synthesized MnONPs were characterized by UV-Vis, XRD, FTIR, SEM-EDX, BET, and zeta potential analyses, which confirmed their crystalline nature, spherical morphology, and mesoporous structure with a surface area of 41.50 m/g.
View Article and Find Full Text PDFBiotechnol J
September 2025
Department of Biochemical Engineering, University College London, London, UK.
Chimeric antigen receptor T-cell (CAR-T) therapies have demonstrated clinical efficacy in treating haematological malignancies, resulting in multiple regulatory approvals. However, there is a need for robust manufacturing platforms and the use of GMP-aligned reagents to meet the clinical and commercial demands. This study investigates the impact of serum/xeno-free medium (SXFM) and cytokine supplementation on CAR-T cell production in static and agitated culture systems, using 24-well plate G-Rex vessels and 500 mL stirred tank bioreactors (STRs), respectively.
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