98%
921
2 minutes
20
Background: The visceral traction response (VTR) occurring during caesarean sections with neuraxial anaesthesia represents a common and significant complication that can greatly affect perioperative results and maternal contentment. Traditional methods for managing VTR frequently face limitations due to differences among individuals, highlighting the necessity for tailored approaches that incorporate personalised risk evaluations, cutting-edge monitoring techniques and enhanced treatment options. Despite the substantial potential of this emerging idea to tackle such an important clinical issue, there is a notable absence of a comprehensive review of the current evidence available.
Objective: This protocol for a scoping review outlines a methodical strategy to chart the existing research landscape related to precision management of VTR in the context of caesarean delivery performed under neuraxial anaesthesia. By developing a conceptual framework, assessing the combined benefits of cutting-edge technologies and summarising tailored intervention techniques, this review aims to pinpoint key attributes, critical areas and new research directions, ultimately contributing to the enhancement of clinical practices and the formulation of rigorous future studies.
Methods: This research will thoroughly follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guidelines. The eligibility criteria will be outlined using the population, concept, context framework. A comprehensive search across various international and Chinese databases (such as PubMed/MEDLINE, Embase, Cochrane Library, Web of Science, CINAHL, Scopus, Google Scholar, China National Knowledge Infrastructure, WanFang and VIP) will be performed for literature published until March 2025, with a final update conducted before submission. Two reviewers will independently assess the literature and extract data. The data will be synthesised in a narrative format, supplemented by tabular and graphical representations, including conceptual framework diagrams and technology application matrices.
Ethics And Dissemination: As this is a secondary analysis of published literature, ethics approval is not required. Results will be disseminated through peer-reviewed publications and presentations at international conferences, establishing an evidence foundation for clinical pathways and guiding future research initiatives. The protocol is registered with the Open Science Framework (https://doi.org/10.17605/OSF.IO/VS94Y).
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12406861 | PMC |
http://dx.doi.org/10.1136/bmjopen-2025-106002 | DOI Listing |
NPJ Biofilms Microbiomes
September 2025
Research Group Medical Systems Biology, University Hospital Schleswig-Holstein Campus Kiel, 24105 Kiel University, Kiel, Schleswig-Holstein, Germany.
Urinary tract infections (UTIs) are among the most common bacterial infections and are increasingly complicated by multidrug resistance (MDR). While Escherichia coli is frequently implicated, the contribution of broader microbial communities remains less understood. Here, we integrate metatranscriptomic sequencing with genome-scale metabolic modeling to characterize active metabolic functions of patient-specific urinary microbiomes during acute UTI.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Inhaled and intranasal corticosteroids are widely used in the management of allergic respiratory diseases. Delayed drug hypersensitivity reactions to budesonide are a rare adverse drug reaction characterized by non-immunoglobulin E (IgE)-mediated clinical manifestations, including localized or systemic contact dermatitis, mucosal edema, and paradoxical worsening of pre-existing symptoms. However, such reactions are often underdiagnosed due to atypical presentations.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Respiratory and Critical Care Medicine, the Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210009, China.
Severe pneumonia, as a critical and prevalent condition of the respiratory system, poses a significant threat to patient survival and health outcomes. This article focuses on the similarities and differences between community-acquired pneumonia (CAP) and hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP). There is significant divergence in the predominant pathogens between severe community-acquired pneumonia (SCAP) and HAP/VAP.
View Article and Find Full Text PDFZhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Pulmonary & Critical Care Medicine, West China Hospital, Sichuan University,Chengdu 600041, China.
Severe pneumonia is a common clinical respiratory disease that is frequently managed by physicians in the Department of Pulmonary and Critical Care Medicine (PCCM). The development of acute respiratory distress syndrome (ARDS) and sepsis are critical factors that contribute to the disease progression and a poor prognosis in severe pneumonia patients. As a key focus in the diagnosis and treatment of critical illnesses, the management of severe pneumonia leverages the strengths of the discipline for pulmonary and critical care physicians.
View Article and Find Full Text PDFBMJ Open
September 2025
Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Introduction: The management of bleeding and coagulation after total knee arthroplasty (TKA) has long been recognised as a significant challenge for orthopaedic surgeons. Despite the notable success of empirical anticoagulation in preventing venous thromboembolism (VTE) following TKA, the increased risk of postoperative bleeding has also raised extensive concern. Ecchymosis, as one of the most common manifestations indicating postoperative bleeding, holds the potential to indicate the balance of bleeding and hypercoagulation.
View Article and Find Full Text PDF