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http://dx.doi.org/10.1016/j.anai.2025.08.017 | DOI Listing |
Int Arch Allergy Immunol
September 2025
Background: Tree nut/Peanut (TN/PN) allergies are among the most common pediatric food allergies, often persisting into later life and posing significant clinical risks. The likelihood of tolerance acquisition varies, and predictive factors remain inadequately defined in clinical practice.
Objective: To evaluate the clinical and laboratory features associated with anaphylaxis risk and tolerance development in pediatric patients with TN/PN allergy, and to determine the role of aeroallergen sensitization, comorbid atopic diseases, and skin test reactivity.
Allergol Immunopathol (Madr)
September 2025
Department of Pediatrics, Ankang Hospital of Traditional Chinese Medicine, Ankang, China;
Allergic asthma is an inflammatory airway disease influenced by genetic and environmental factors and orchestrated by imbalance between T helper 1 cell (Th1) and two immune responses. Inflammation contributes to pathological changes and remodeling in tissues such as the vascular, lung, heart, and beds. The purpose for this study was to evaluate the effects of allergic asthma on heart pathology and remodeling.
View Article and Find Full Text PDFAllergol Immunopathol (Madr)
September 2025
Department of Pediatric Allergy and Clinical Immunology, Başakşehir Çam and Sakura City Hospital, Istanbul, Türkiye.
Purpose: We aimed to investigate allergic sensitization and associated factors in pediatric patients with selective immunoglobulin A deficiency (SIgAD) and to evaluate differences between allergic and nonallergic groups.
Methods: We analyzed 110 patients (aged 4-18 years) diagnosed with SIgAD at Çam and Sakura City Hospitals, Istanbul, between 2021 and 2024. Their demographic, clinical, and laboratory data were assessed.
Allergol Immunopathol (Madr)
September 2025
Special Hospital for Pulmonary Diseases, Zagreb, Croatia.
Penicillin allergy is the most commonly reported drug allergy, often leading to unnecessary avoidance of beta-lactam antibiotics, increased use of alternative broad-spectrum antibiotics, and higher healthcare costs. However, studies indicate that over 90% of penicillin allergy labels are erroneous. This study presents real-world data from a penicillin allergy delabeling program conducted at the Special Hospital for Pulmonary Diseases in Zagreb, Croatia.
View Article and Find Full Text PDFEar Nose Throat J
September 2025
Department of Otorhinolaryngology-Head and Neck Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Background: Mouth breathing (MB) is a pediatric public health concern potentially increasing dental caries risk. We investigated risk factors, relationships between clinical characteristics and medical costs, and their effects on caries severity.
Study Design: Observation study.