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Introduction Flexion contracture of the knee has been reported to induce forward trunk inclination and pelvic retroversion, whereas the progression of pelvic retroversion may further exacerbate knee joint symptoms, suggesting a close relationship between the knee and spinal alignment. The purpose of this study was to investigate the effects of lower limb alignment changes after opening wedge high tibial osteotomy (OWHTO) on spinopelvic sagittal alignment. Methods We retrospectively analyzed 34 knees that underwent OWHTO for medial compartment knee osteoarthritis between 2023 and 2025. Standing full-length lower limb and whole-spine radiographs were obtained preoperatively and at one year postoperatively. Lower limb alignment parameters, i.e., the percentage of mechanical axis (MA), mechanical medial proximal tibial angle (mMPTA), mechanical lateral distal femoral angle (mLDFA), joint line convergence angle (JLCA), and posterior tibial slope (PTS), were evaluated. Spinopelvic parameters included pelvic tilt (PT), sacral slope (SS), pelvic incidence (PI), thoracic kyphosis (TK), lumbar lordosis (LL), and the mismatch between PI and LL (PI-LL) Clinical outcomes were assessed using the Knee Injury and Osteoarthritis Outcome Score (KOOS) before surgery and at one year postoperatively. Correlations between postoperative spinopelvic parameters and clinical outcomes were also examined. Results Pelvic tilt and the mismatch between PI and LL significantly decreased following OWHTO (p = 0.003 and p = 0.044, respectively), indicating improvement in spinopelvic sagittal alignment. However, no significant correlations were found between changes in spinal alignment and postoperative scores on the KOOS. Conclusion Both pelvic tilt and the mismatch between PI and LL, which reflect lumbopelvic alignment, were significantly decreased after OWHTO. This may have arisen because the correction of knee alignment improved the load distribution in the lower limbs, which in turn contributed to the improvement of lumbopelvic alignment. Our findings suggest that OWHTO not only corrects lower limb alignment but may also have a positive effect on lumbopelvic alignment.
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http://dx.doi.org/10.7759/cureus.89173 | DOI Listing |
IEEE Trans Biomed Circuits Syst
September 2025
Neuroprostheses capable of providing Somatotopic Sensory Feedback (SSF) enables the restoration of tactile sensations in amputees, thereby enhancing prosthesis embodiment, object manipulation, balance and walking stability. Transcutaneous Electrical Nerve Stimulation (TENS) represents a primary noninvasive technique for eliciting somatotopic sensations. Devices commonly used to evaluate the effectiveness of TENS stimulation are often bulky and main powered.
View Article and Find Full Text PDFJ Cardiovasc Surg (Torino)
September 2025
Catheterization Laboratory, Montevergine Clinic, Mercogliano, Avellino, Italy -
Background: Lower extremity arterial disease is a prevalent vascular condition leading to ischemic symptoms and increased risk of cardiovascular events. Drug-eluting stents have improved outcomes by reducing restenosis, with sirolimus emerging as a promising alternative to paclitaxel due to its safer profile. This study evaluates the efficacy and safety of novel polymer-free Amphilimus formulation (Sirolimus + fatty acid) eluting self-expanding stent in the treatment of femoropopliteal disease in a real-world population.
View Article and Find Full Text PDFLangenbecks Arch Surg
September 2025
Department of Surgery (A), Medical Faculty, Heinrich-Heine-University, University Hospital Duesseldorf, Duesseldorf, Germany.
Introduction: Remote ischaemic preconditioning (RIPC) which consists of repeated brief episodes of non-lethal limb ischaemia is associated with organ protection and improved clinical outcomes through complex pathophysiological pathways. The aim of this meta-analysis was to evaluate the postoperative effects of RIPC in bowel recovery and surgical morbidity after colorectal surgery.
Methods: In strict adherence to the PRISMA guidelines, a systematic literature search was performed for studies comparing the postoperative effect RIPC in colorectal surgery.
Khirurgiia (Mosk)
September 2025
Mandryka Central Military Clinical Hospital, Moscow, Russia.
Widespread fragmentation shells in combat operations with frequent multiple damage to organs and systems force to use all available diagnostic methods for treating severe injuries including lesion of great vessels of extremities. One of the consequences of these lesions is arteriovenous fistula (AVF). The last one may be asymptomatic at first.
View Article and Find Full Text PDFKhirurgiia (Mosk)
September 2025
Sklifosovsky Research Institute for Emergency Care, Moscow, Russia.
Objective: To analyze and improve postoperative outcomes in patients with acute lower limb ischemia (ALLI) and previous reconstructive infrainguinal interventions.
Material And Methods: The authors analyzed postoperative outcomes after 54 repeated interventions in patients with thrombosis of common femoral artery bifurcation, deep femoral artery and non-functioning femoropopliteal (tibial) prosthesis.
Results: External-iliac-deep femoral replacement were performed in 28 (52%) patients, extended deep femoral artery repair - in 16 (29.