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[This corrects the article DOI: 10.7759/cureus.90770.].
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Background Cerebral autoregulation is a homeostatic process that maintains constant cerebral blood flow during hypotension produced by spinal anesthesia. Beyond the auto-regulation range of mean blood pressure (MBP), the brain is vulnerable to ischemia and hyperperfusion-induced cerebral edema when blood pressure is above the auto-regulatory threshold. Spinal hypotension may cause a fall in regional cerebral oxygenation (C-rSO₂) below the lower limit of autoregulation in some patients.
View Article and Find Full Text PDF[This corrects the article DOI: 10.7759/cureus.90770.
View Article and Find Full Text PDFCalculation of effective dose of phenylephrine bolus for treatment of post-spinal hypotension in pre-eclamptic patients undergoing caesarean section - a non-randomised controlled trial.
Int J Obstet Anesth
November 2023
Department of Obstetrics and Gynaecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
Background: Patients with pre-eclampsia require smaller vasopressor doses compared with those with normotension for management of post-spinal hypotension during caesarean section. However, the literature has little evidence as to the phenylephrine dose required for patients with pre-eclampsia.
Methods: Fifty patients, with either pre-eclampsia or normotension, and developing post-spinal hypotension during caesarean section under spinal anaesthesia, were studied.
Investigating acetazolamide effectiveness on CSF leak in adult patients after spinal surgery.
Neurocirugia (Engl Ed)
November 2022
Department of Neurosurgery, School of Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:
Introduction And Objectives: Despite the use of acetazolamide in the management of CSF leak in most patients after CNS surgeries, there is scant evidence in the literature about the efficacy of this established protocol among adult patients in post-spinal surgery observations. We investigated the potential positive effect of acetazolamide in reducing CSF leak after spine surgery.
Materials And Methods: We conducted a single-center, double-blind, randomized -controlled trial comparing Oral Acetazolamide plus Corrected body (prone) position (CP+A) versus Corrected body (prone) position alone (CP-A) from January 2014 to September 2015 in the Neurosurgery ward of Shariati Teaching Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Definitive fusion for scoliosis in late juvenile cerebral palsy patients is durable at 5 years postoperatively.
Spine Deform
November 2022
Department of Orthopedics and Sports Medicine, Seattle Children's Hospital, M/S OA.9.120, 4800 Sandpoint Way NE, Seattle, WA, 98105, USA.
Purpose: Given the challenges associated with managing progressive scoliosis in patients with cerebral palsy (CP), the purpose of this study was to evaluate deformity correction and HRQOL 5 years post-spinal fusion in CP patients who were skeletally immature at the time of surgical correction.
Methods: CP patients who underwent definitive fusion before age 11 with minimum 5-years follow-up from a prospective, multicenter registry were included. Preoperative, initial postoperative, and 5-years radiographic data were collected.