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Aortoenteric fistula (AEF) is a rare but catastrophic complication following esophagectomy, often resulting in massive upper gastrointestinal bleeding and high mortality. While most cases occur early in the postoperative period, delayed presentations remain poorly understood. We report the case of a 54-year-old woman who underwent esophagectomy and gastric pull-up for mid-esophageal squamous cell carcinoma. Nine months postoperatively, the patient presented with hematemesis, hemorrhagic shock, and died despite resuscitative efforts. Autopsy revealed a 0.9 cm erosion in the descending thoracic aorta with adjacent ulceration of the gastric conduit and bacterial infiltration consistent with a thoracic AEF. This case illustrates a rare, delayed presentation of AEF confirmed by post-mortem analysis. It highlights the need for ongoing clinical vigilance even in patients with initially uncomplicated recoveries.
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http://dx.doi.org/10.1093/jscr/rjaf674 | DOI Listing |
Rev Med Interne
September 2025
Service d'hématologie biologique, CHU d'Amiens-Picardie, Amiens, France; HEMATIM UR4666, université Picardie Jules-Verne, Amiens, France.
The diagnosis of hemolysis is still based on straightforward biochemical parameters: haptoglobin (the most sensitive), lactate dehydrogenase (LDH), and unconjugated bilirubin. Anemia is not always present. Reticulocyte counts typically exceed 120×10/L, except in cases of associated vitamin deficiency or during the very early phase of acute hemolysis.
View Article and Find Full Text PDFJ Anat
September 2025
Cátedra de Biología General, Facultad de Ciencias Naturales e Instituto Miguel Lillo, Universidad Nacional de Tucumán, San Miguel de Tucumán, Argentina.
The knee joint plays a critical role in tetrapod locomotion, yet its developmental trajectories and anatomical diversity remain underexplored outside of model taxa. Here, we examine knee joint development in three representative reptilian lineages, Phrynops hilarii (Testudines), Caiman latirostris (Crocodylia), and Columba livia (Aves), and compare them with adult knee morphology in two squamate species, Cercosaura parkerii and Hemidactylus mabouia. Using histological series spanning key developmental stages, we document patterns of ossification, meniscus formation, cartilage composition, and sesamoid presence.
View Article and Find Full Text PDFBMJ Case Rep
September 2025
Department of Pathology and Lab Medicine, All India Institute of Medical Sciences Jodhpur, Jodhpur, Rajasthan, India.
Gaucher's disease (GD) is the most common lysosomal storage disorder inherited in an autosomal recessive pattern. It occurs due to a deficiency of the enzyme glucocerebrosidase owing to a mutation in the acid-β-glucosidase () gene resulting in accumulation of glucocerebrosides in lysosomes of cells. It presents with abdominal distension, hepatosplenomegaly, developmental delay, pancytopenia, neurological manifestations and bone diseases.
View Article and Find Full Text PDFMath Biosci
September 2025
Department of Mathematics, Western University, London, Ontario, N6A 5B7, Canada. Electronic address:
Pine wilt disease (PWD) is mainly spread by Monochamus alternatus (in short, M. alternatus). Woodpecker, as the natural predator of M.
View Article and Find Full Text PDFArch Cardiol Mex
September 2025
Departamento de Cardiología Pediátrica, Instituto Nacional de Pediatría, Ciudad de México. México.
Introduction: Patients with aortic coarctation frequently present a delay in diagnosis mainly in newborns and infants, since the respiratory symptoms predominate in this age group. The absence of an adequate physical examination, with emphasis on the palpation of the pulses in the four extremities, in addition to the absence to obtain of blood pressure, condemns these patients to a fortuitous finding or event before the diagnosis can be made.
Method: Retrospective, descriptive and observational study.