Severity: Warning
Message: file_get_contents(https://...@gmail.com&api_key=61f08fa0b96a73de8c900d749fcb997acc09&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
Filename: helpers/my_audit_helper.php
Line Number: 197
Backtrace:
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 197
Function: file_get_contents
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 271
Function: simplexml_load_file_from_url
File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3165
Function: getPubMedXML
File: /var/www/html/application/controllers/Detail.php
Line: 597
Function: pubMedSearch_Global
File: /var/www/html/application/controllers/Detail.php
Line: 511
Function: pubMedGetRelatedKeyword
File: /var/www/html/index.php
Line: 317
Function: require_once
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Thumb-in-palm deformity significantly limits hand function in arthrogryposis multiplex congenita (AMC), resulting from intricate interactions between contracted thumb-index web skin, restrictive intrinsic musculature, joint instability, and compromised extrinsic tendons, collectively causing thumb adduction, flexion, and poor opposition. Due to the complexity of this deformity, surgical outcomes have historically varied. We introduced a severity-based classification system-mild, moderate, or severe-to guide treatment decisions. Mild cases were addressed conservatively, moderate cases underwent single-stage reconstructive surgery, and severe deformities required two-stage procedures, sometimes addressing concurrent finger contractures. A preliminary clinical series involving 16 thumbs demonstrated promising results, with the majority achieving excellent functional outcomes as assessed by a modified Gilbert grading system. Minimal complications were noted. Our structured surgical strategy based on deformity severity enhances functional recovery, allowing tailored management and improved consistency of outcomes.
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Source |
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395147 | PMC |
http://dx.doi.org/10.1016/j.jcot.2025.103179 | DOI Listing |