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Article Abstract
Background: This study aimed to compare the clinical efficacy and prognosis of transcervical resection of polyp (TCRP) combined with levonorgestrel-releasing intrauterine system (LNG-IUS) or oral desogestrel and ethinyl estradiol tablets (DET) in patients with endometrial polyps (EMP).
Methods: A total of 100 EMP patients undergoing TCRP were divided into LNG-IUS ( = 50) and DET ( = 50) groups. Hemoglobin, endometrial thickness, FSH, E2, and LH levels were monitored pre-surgery and post-surgery. Clinical symptom improvement, adverse reactions, and recurrence rates were assessed over 12 months.
Results: Both treatments improved hemoglobin levels and reduced endometrial thickness, but the LNG-IUS group showed superior outcomes. At 12 months, it achieved higher improvement rates for dysmenorrhea (72.0% vs. 34.0%), abnormal cycles (60.0% vs. 24.0%), and blood loss (52.0% vs. 30.0%), with fewer adverse reactions (4.0% vs. 24.0%) and a lower recurrence rate (0% vs. 16.0%, all < .05).
Conclusions: LNG-IUS with TCRP outperformed DET in reducing endometrial thickness, alleviating symptoms, lowering side effects, and preventing recurrence in EMP.
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| http://dx.doi.org/10.1080/13645706.2025.2542329 | DOI Listing |
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