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Precise and rapid identification of knee osteoarthritis (OA) is essential for efficient management and therapy planning. Conventional diagnostic techniques frequently depend on subjective interpretation, which have shortcomings, particularly during the first phases of the illness. In this study, magnetic resonance imaging (MRI) was used to create knee datasets as novel techniques for evaluating knee OA. This methodology utilizes artificial intelligence (AI) algorithms to identify and evaluate important indications of knee osteoarthritis, including osteophytes, eburnation, bone marrow lesions (BMLs), and cartilage thickness. We conducted training and evaluation on multiple deep learning models, including ResNet50, DenseNet121, VGG16 and ResNet101 utilizing annotated MRI data. By conducting thorough statistical analysis and validation, we have proven the efficacy of our models in precisely diagnosing and grading knee OA. This research presents a new grading method, verified by experienced radiologists, that uses eburnation as a significant indicator of the severity of knee OA. This study provides a new method for an AI-powered automated system designed to diagnose knee OA. This system will simplify the diagnostic process, minimize mistakes made by humans, and enhance the effectiveness of clinical treatment. Through the integration of AI-ML (machine learning) technologies, our goal is to improve patient outcomes, optimize the utilization of healthcare resources, and enable personalized knee OA therapy.
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http://dx.doi.org/10.1039/d5bm00470e | DOI Listing |
Cureus
August 2025
Department of Orthopedic Surgery, Matsuda Orthopedic Clinic, Kumagaya, JPN.
Background: The effect of supplementation of essential amino acids (EAAs) in knee osteoarthritis (OA) remains unclear. This study aimed to evaluate whether supplementation with EAA improves pain, patient-reported outcome measures, gait function, and quadriceps muscle volume in patients undergoing conservative treatment for knee OA.
Methods: A retrospective cohort study was conducted on outpatients undergoing physical therapy from April 2024 to March 2025.
BMJ Open
September 2025
Department of Orthopaedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
Introduction: The management of bleeding and coagulation after total knee arthroplasty (TKA) has long been recognised as a significant challenge for orthopaedic surgeons. Despite the notable success of empirical anticoagulation in preventing venous thromboembolism (VTE) following TKA, the increased risk of postoperative bleeding has also raised extensive concern. Ecchymosis, as one of the most common manifestations indicating postoperative bleeding, holds the potential to indicate the balance of bleeding and hypercoagulation.
View Article and Find Full Text PDFInt J Orthop Trauma Nurs
August 2025
Autoimmune Diseases Research Center, Kashan University of Medical Sciences, Kashan, Iran. Electronic address:
Background: Knee osteoarthritis (KOA) is a prevalent degenerative joint disorder that significantly impairs physical function and daily activities. While conventional treatments focus on symptom management, complementary therapies such as aromatherapy massage have gained attention for their potential benefits.
Objective: This study evaluates the effects of peppermint oil aromatherapy massage on functional impairments in KOA patients.
Physiother Theory Pract
September 2025
School of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan, ROC.
Background: Knee osteoarthritis (OA) causes pain and diminishes quality of life. Backward walking exercise (BWE) has been shown to improve lower muscle strength and reduce knee adduction moment, making it a recommended intervention for knee OA rehabilitation. This study aims to evaluate the effectiveness of BWE combined with conventional rehabilitation programs on pain intensity and disability among individuals with knee OA.
View Article and Find Full Text PDFClin J Sport Med
September 2025
Western University, London, Ontario, Canada.
Objective: Anterior cruciate ligament reconstruction (ACLR) leads to high rates of knee post-traumatic osteoarthritis (PTOA). Physical activity may mitigate PTOA risk but levels after ACLR have not been extensively studied. We aimed to review self-reported and device-measured physical activity levels in individuals with ACLR and compare them with international guidelines, and with uninjured controls.
View Article and Find Full Text PDF