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http://dx.doi.org/10.1093/eurheartj/ehaf651 | DOI Listing |
Eur Heart J
August 2025
Department of Cardiology, Maastricht University Medical Centre and Cardiovascular Research Institute Maastricht, Maastricht 6229 HX, The Netherlands.
Eur Heart J
August 2025
Department of Cardiology, Copenhagen University Hospital-Rigshospitalet, Inge Lehmanns Vej 7, Copenhagen 2100, Denmark.
Background And Aims: Potassium levels influence cardiac electrophysiology, yet their day-to-day association with atrial fibrillation (AF) remains unclear. This study investigated the association between plasma potassium (p-potassium) and daily AF in at-risk individuals undergoing continuous electrocardiographic monitoring.
Methods: This is a post hoc analysis of the LOOP study randomizing participants with stroke risk factors to implantable loop recorder (ILR) screening for AF (n = 1501) or usual care.
JCEM Case Rep
October 2025
Department of Critical Care Medicine, Sheikh Shakhbout Medical City, P. O. Box 11001, Abu Dhabi, UAE.
Thyrotoxic periodic paralysis (TPP) is a rare and potentially life-threatening disorder characterized by transient muscle weakness due to hypokalemia in the setting of hyperthyroidism. We present a case of a 32-year-old male with no prior history of thyroid disease who developed acute, progressive paralysis of all 4 extremities. Laboratory findings revealed profound hypokalemia, hypophosphatemia, and elevated lactate.
View Article and Find Full Text PDFEuropace
August 2025
Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No. 100 Ziyou 1st Rd, Kaohsiung 80756, Taiwan.
Aims: Metabolic syndrome (MetS) increases the risk of atrial arrhythmias (AA). Hypokalaemia, often secondary to diuretics or diet, frequently coexists with MetS and influences calcium handling. This study investigates the role of apamin-sensitive small-conductance calcium-activated potassium (SK) channels in atrial arrhythmogenesis under hypokalaemic MetS conditions.
View Article and Find Full Text PDFFront Psychiatry
July 2025
Department of Pharmacy, HuZhou Central Hospital, The Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Huzhou, China.
Background: While clomipramine is generally considered lower risk for QT prolongation among tricyclic antidepressants, its potential to induce torsades de pointes (TdP) remains poorly characterized, particularly in patients with multiple risk factors.
Case Presentation: A 78-year-old male with a history of hypertension, atrial fibrillation, and post-stroke depression presented to the emergency department with a one-week history of chest distress. Initial evaluation revealed atrial fibrillation with a prolonged QTc interval of 550 ms on electrocardiogram (ECG) monitoring, and elevated B-type natriuretic peptide (1130 pg/mL).