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Background: During the COVID-19 pandemic, youth experienced disruptions in their social development due to social distancing mandates. Research evaluating effects of isolation on adolescent mental health and eating disorders demonstrated increased ED visits during COVID. The goal of this study was to examine the effect of the COVID-19 pandemic on the number of eating disorder admissions at a large pediatric inpatient eating disorder unit and on illness severity.
Methods: We conducted a retrospective chart review of patients admitted to a pediatric inpatient eating disorder unit from January 2019 through December 2021. Differences in number of admissions and patient characteristics were compared before and after the start of the COVID-19 stay-at-home mandate (i.e., "outbreak"). Interrupted time series analysis compared monthly admission trends pre- and post-outbreak. Logistic and linear regression models were created to evaluate differences in severity.
Results: There were 143 patients admitted pre-outbreak and 314 patients admitted post-outbreak (84% female, 26.3% publicly insured, median age 15 years). There was a significant increase in the mean number of admissions per month post-outbreak (10.21, [SD 3.36] vs. 14.27 [SD 3.31], p < 0.01). Trends in admissions per month were stable prior to the COVID-19 outbreak (β = -0.38, p = 0.07) and increased after the start of the outbreak (β = 0.63, p < 0.01). Patients pre-outbreak had lower mean systolic blood pressures than post-outbreak (β = -1.90 [SE 0.82], p = 0.02). The odds of hypophosphatemia were lower post-outbreak (OR 0.42 [95% CI 0.21-0.81]).
Conclusions: Clinical characteristics on admission were less severe post-outbreak. Closures of outpatient treatment programs may have led to lower acuity patients being hospitalized. Preserving access to robust outpatient eating disorder treatment may prevent this phenomenon during future public health crises.
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http://dx.doi.org/10.1186/s40337-025-01385-w | DOI Listing |
Brain Behav
September 2025
The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China.
Background: Diverse correlations between structural brain abnormalities and the clinical feature of bulimia nervosa (BN) have been identified in previous observational studies.
Objective: To explore the bidirectional causality between BN and brain structural magnetic resonance imaging (MRI) phenotypes.
Methods: Genome-wide association studies (GWAS) of 2441 participants identified genetic variants associated with disordered eating and predicted BN, whereas UK Biobank 3D-T1 MRI data were used to analyze brain structural phenotypes.
Int Dent J
September 2025
Center of Excellence in Precision Medicine and Digital Health, Geriatric Dentistry and Special Patients Care International Program, Department of Physiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand; Clinic of General - Special Care and Geriatric Dentistry, Center for Dental
Background: Emerging evidence suggests a link between the oral microbiome and autism spectrum disorder (ASD), a neurodevelopmental condition characterised by social and behavioural impairments. The vast microbial reservoirs in the gut complement those of the oral cavity, suggesting a potential oral-gut-brain axis that may influence ASD and perhaps other neurological diseases, such as Parkinson's syndrome and Alzheimer's disease. For the first time, this systematic review synthesises the current knowledge of oral microbiome composition, diversity, and functionality in ASD and its potential diagnostic and therapeutic implications.
View Article and Find Full Text PDFNeuro Endocrinol Lett
September 2025
Department of Pediatric Neurology, Cukurova University Faculty of Medicine, Adana, Turkey.
Objective: It is important to raise awareness of the nutritional problems that can be overlooked during the follow-up visits with children who suffer from neuromuscular diseases, as these dietary differences may lead to additional neurological and systemic problems and impair the quality of life of the patient. The aim of this study was to evaluate the nutritional status of children with neuromuscular disorders and to prevent possible complications by recognizing possible nutritional problems in advance.
Methods: Patients who applied to the outpatient clinic at Cukurova University, Faculty of Medicine, Department of Pediatric Neurology beginning in April 2022 with a neuromuscular disorder diagnosis were followed up with and were included in the study.
PLoS One
September 2025
Department of Health Promotion, Education and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina, United States of America.
This study aimed to examine how trust in institutions and changes in household finances were associated with healthcare utilization and preventive behaviors during and immediately after the COVID-19 pandemic. The COVID-19 pandemic worsened health disparities, ignited distrust in healthcare systems, and contributed to household economic shifts for many United States (US) residents. To examine these issues, we surveyed a nationally representative sample of US residents in July 2020 (n = 1,085) and May 2023 (n = 2,189).
View Article and Find Full Text PDFEat Disord
September 2025
Department of Psychology, University of North Dakota, Grand Forks, North Dakota, USA.
Yoga is associated with improvements in factors that protect against the development of eating disorders (EDs), such as mindfulness, self-compassion, and body appreciation. Additionally, yoga is associated with lower body dissatisfaction (BD) and disordered eating. However, research on how yoga reduces BD and ED symptoms is limited.
View Article and Find Full Text PDF